Tiparp - TCDD-inducible poly(ADP-ribose) polymerase Gene

Rattus norvegicus

Also known as RM1

Gene ID: 310467 | Gene type: protein coding

About Tiparp

Primary_assembly 2: 149,753,682-149,780,327 forward strand.mRatBN7.2:CM026975.1

This gene has 2 transcripts (splice variants), 208 orthologues, 7 paralogues and is associated with 1 phenotype. Biased expression in Heart (RPKM 15.5), Lung (RPKM 117.2) and 9 other tissues.

Summary

Predicted to enable NAD+ ADP-ribosyltransferase activity; cis-regulatory region sequence-specific DNA binding activity; and protein ADP-ribosylase activity. Involved in response to 2,3,7,8-tetrachlorodibenzodioxine. Predicted to be located in nucleus. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase). [provided by Alliance of Genome Resources, Apr 2022]

Tiparp Products(2)

mRNA	Protein	Name
NM_001107679.3	NP_001101149.2	protein mono-ADP-ribosyltransferase TIPARP
NM_001107679.3	NP_001101149.2	protein mono-ADP-ribosyltransferase TIPARP

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in response to 2,3,7,8-tetrachlorodibenzodioxine	IEP IEP: Inferred from expression pattern	24355419	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Tiparp Protein Structure

WWE

TCCD_inducible_PARP_like

0
200
400
600
657 a.a.

Protein Preferred Names

Protein Names

protein mono-ADP-ribosyltransferase TIPARP

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14546	TIPARP Human Pre-designed siRNA Set A	/	Unkown
HY-RS14547	Tiparp Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS14548	Tiparp Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tiparp	NCBI	NCBI:25976

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