Mdga2 - MAM domain containing glycosylphosphatidylinositol anchor 2 Gene

Mus musculus

Also known as Adp; Mamdc1; 6720489L24Rik; 9330209L04Rik; Tg(Prnp-PFN1*G118V)838Kiaei

Gene ID: 320772 | Gene type: protein coding

About Mdga2

Summary

Involved in regulation of presynapse assembly and regulation of synaptic membrane adhesion. Acts upstream of or within neuron migration and pattern specification process. Located in GABA-ergic synapse. Is active in glutamatergic synapse. Orthologous to human MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2). [provided by Alliance of Genome Resources, Apr 2022]

Mdga2 Products(2)

mRNA	Protein	Name
NM_001193266.1	NP_001180195.2	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform A precursor
NM_207010.2	NP_996893.3	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform B precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23358245	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within gene expression	IMP IMP: Inferred from mutant phenotype	30213953	MGI
acts upstream of or within motor behavior	IMP IMP: Inferred from mutant phenotype	29518482	MGI
acts upstream of or within negative regulation of neuron apoptotic process	IMP IMP: Inferred from mutant phenotype	29518482	MGI
acts upstream of or within neuromuscular process	IMP IMP: Inferred from mutant phenotype	29518482	MGI
acts upstream of or within neuron migration	IDA IDA: Inferred from direct assay	25162227	MGI
acts upstream of or within pattern specification process	IMP IMP: Inferred from mutant phenotype	1633717	MGI
involved in regulation of presynapse assembly	IDA IDA: Inferred from direct assay	27608760	MGI
involved in regulation of presynapse assembly	IMP IMP: Inferred from mutant phenotype	27608760	MGI
involved in regulation of synaptic membrane adhesion	IDA IDA: Inferred from direct assay	27608760	MGI
involved in regulation of synaptic membrane adhesion	IMP IMP: Inferred from mutant phenotype	27608760	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in GABA-ergic synapse	IDA IDA: Inferred from direct assay	27608760	MGI
is active in GABA-ergic synapse	IMP IMP: Inferred from mutant phenotype	27608760	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	27608760	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	27608760	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

MAM domain-containing glycosylphosphatidylinositol anchor protein 2

MAM domain containing 1

acrodysplasia

Recombinant Mdga2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77082	MDGA2 Protein, Mouse (HEK293, His)	P60755 (P26-D924)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08259	MDGA2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mdga2	NCBI	NCBI:161357

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