2. Gene
  3. PPM1J - protein phosphatase, Mg2+/Mn2+ dependent 1J Gene

PPM1J - protein phosphatase, Mg2+/Mn2+ dependent 1J Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PP2CZ; PPP2CZ; PP2Czeta; PP2C-zeta

Gene ID: 333926 | Gene type: protein coding

About PPM1J

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,709,998-112,715,332 (from NCBI)

This gene has 5 transcripts (splice variants), 504 orthologues and 16 paralogues. Biased expression in testis (RPKM 22.7), skin (RPKM 8.1) and 5 other tissues.

Summary

This gene encodes the serine/threonine protein Phosphatase. The mouse homolog of this gene apparently belongs to the protein Phosphatase 2C family of genes. The exact function of this gene is not yet known. [provided by RefSeq, Jul 2008]

PPM1J Products(1)

mRNA Protein Name
NM_005167.7 NP_005158.5 protein phosphatase 1J
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PPM1J Protein Structure

PP2C

PP2C: Protein phosphatase 2C (218 - 307)

PP2C

PP2C: Protein phosphatase 2C (370 - 453)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 505 a.a.
Protein Preferred Names Protein Names

protein phosphatase 1J

protein phosphatase 1J (PP2C domain containing)

PPM1J Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra PPM1J Q5JR12 LGALS14 Homo sapiens Q8TCE9
Validated Y2H
32296183
Intra PPM1J Q5JR12 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
Intra PPM1J Q5JR12 SPG21 Homo sapiens Q9NZD8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10967 PPM1J Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PPM1J VGNC VGNC:76086
Rattus norvegicus PPM1J RGD RGD:1359104
Bos taurus PPM1J VGNC VGNC:54471
Canis familiaris PPM1J VGNC VGNC:44869
Felis catus PPM1J VGNC VGNC:64313
Mus musculus PPM1J MGD MGI:1919137