ST8SIA6 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Gene

Homo sapiens

Also known as SIA8F; SIAT8F; SIAT8-F; ST8SiaVI; ST8SIA-VI

Gene ID: 338596 | Gene type: protein coding

About ST8SIA6

Cytogenetic location: 10p12.33 Genomic coordinates (GRCh38): 10:17,315,421-17,454,595 (from NCBI)

This gene has 3 transcripts (splice variants), 125 orthologues and 5 paralogues. Broad expression in lung (RPKM 3.3), heart (RPKM 1.0) and 14 other tissues.

Summary

This gene encodes a member of the Glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in Cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

ST8SIA6 Products(2)

mRNA	Protein	Name
NM_001004470.3	NP_001004470.1	alpha-2,8-sialyltransferase 8F isoform 1 precursor
NM_001345961.2	NP_001332890.1	alpha-2,8-sialyltransferase 8F isoform 2

ST8SIA6 Protein Structure

Glyco_transf_29

0
100
200
300
398 a.a.

Protein Preferred Names

Protein Names

alpha-2,8-sialyltransferase 8F

ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 6

Related Diseases

Diseases

Alias

Lice Infestation

Pediculosis	Louse Infestation
Mixed Pediculosis	Lice Infestations
Infestation By Pediculus	Mixed Pediculosis Infestation
Pediculosis + Lice	Pediculosis And Phthirus Infection
Pediculosis And Phthirus Infections	Pediculosis And Phthirus Infestation
Infestation By Anoplura	Pediculus Infestation
Lice Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-E70302	ST8 alpha-2,8-Sialyltransferase 6		/	Unkown
HY-RS13860	ST8SIA6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ST8SIA6	MGD	MGI:2386797
Rattus norvegicus	ST8SIA6	RGD	RGD:1303161
Bos taurus	ST8SIA6	VGNC	VGNC:35347
Canis familiaris	ST8SIA6	VGNC	VGNC:46868

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