LUZP2 - leucine zipper protein 2 Gene

Homo sapiens

Also known as PRO6246; KFSP2566

Gene ID: 338645 | Gene type: protein coding

About LUZP2

Cytogenetic location: 11p14.3 Genomic coordinates (GRCh38): 11:24,497,053-25,082,638 (from NCBI)

This gene has 8 transcripts (splice variants) and 198 orthologues. Biased expression in brain (RPKM 5.0), adrenal (RPKM 1.6) and 1 other tissue.

Summary

This gene encodes a leucine zipper protein. This protein is deleted in some patients with Wilms tumor-Aniridia-Genitourinary anomalies-mental Retardation (WAGR) syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

LUZP2 Products(3)

mRNA	Protein	Name
NM_001009909.4	NP_001009909.2	leucine zipper protein 2 isoform 1 precursor
NM_001252008.2	NP_001238937.1	leucine zipper protein 2 isoform 2
NM_001252010.2	NP_001238939.1	leucine zipper protein 2 isoform 3

LUZP2 Protein Structure

Leu_zip

0
100
200
300
346 a.a.

Protein Preferred Names

Protein Names

leucine zipper protein 2

Related Diseases

Diseases

Alias

Albinism, Oculocutaneous, Type Ii

OCA2	Oculocutaneous Albinism Type 2
Oculocutaneous Albinism Type Ii	Albinoidism
Tyrosinase-Positive Oculocutaneous Albinism	Brown Oculocutaneous Albinism
Oculocutaneous Albinism, Tyrosinase-Positive	Albinism Ii
Albinism, Brown Oculocutaneous	Oculocutaneous Albinism, Type Ii, Modifier Of
Oculocutaneous Albinism, Type Ii	Albinism, Oculocutaneous, Type Ii, Modifier Of
Albinism 2	Albinism, Oculocutaneous, Type 2
Oculocutaneous Albinism Tyrosinase Positive	Oculocutaneous Albinism, Tyrosinase Positive
Albinism, Oculocutaneous, 2	Boca
Oca-2	Oculocutaneous Albinism Tyrosinase-Positive

Aniridia 1

Aniridia	Congenital Aniridia
AN1	An
Cataract With Late-Onset Corneal Dystrophy	Aplasia Of Iris
Absent Iris	Irideremia
Aniridia Ii, Formerly	An2, Formerly
An2	Aniridia Type Ii
Aniridia, Type 1	An-1
Absence Of Iris	Agenesis Of Iris
Congenital Absence Of Iris	Hereditary Aniridia
Sporadic Aniridia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07893	LUZP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	LUZP2	VGNC	VGNC:42869
Rattus norvegicus	LUZP2	RGD	RGD:6496163
Felis catus	LUZP2	VGNC	VGNC:63331
Macaca mulatta	LUZP2	VGNC	VGNC:74336
Bos taurus	LUZP2	VGNC	VGNC:31085
Mus musculus	LUZP2	MGD	MGI:1889615

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