GADL1 - glutamate decarboxylase like 1 Gene

Homo sapiens

Also known as ADC; CSADC; HuADC; HuCSADC

Gene ID: 339896 | Gene type: protein coding

About GADL1

Cytogenetic location: 3p24.1-p23 Genomic coordinates (GRCh38): 3:30,726,197-30,894,661 (from NCBI)

This gene has 3 transcripts (splice variants), 193 orthologues and 7 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable aspartate 1-decarboxylase activity; pyridoxal phosphate binding activity; and sulfinoalanine decarboxylase activity. Predicted to be involved in carboxylic acid metabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

GADL1 Products(1)

mRNA	Protein	Name
NM_207359.3	NP_997242.2	acidic amino acid decarboxylase GADL1

GADL1 Protein Structure

Pyridoxal_deC

0
100
200
300
400
521 a.a.

Protein Preferred Names

Protein Names

acidic amino acid decarboxylase GADL1

aspartate 1-decarboxylase

Related Diseases

Diseases

Alias

Bainbridge-Ropers Syndrome

BRPS	Severe Feeding Difficulties-Failure To Thrive-Microcephaly Due To Asxl3 Deficiency Syndrome
Asxl3-Related Disorder

Bipolar I Disorder

Manic Depression Nos	Manic-Depressive Illness
Bipolar Disorder Nos

Bipolar Disorder

Bipolar Depression	Manic Disorder
Depression, Bipolar	Bipolar Disorder Manic Phase
Depressive-Manic Psych.	Manic Bipolar Affective Disorder
Manic Bipolar I Disorder	Manic Depression
Manic Depressive Disorder	Mixed Bipolar Disorder
Bipolar Affective Disorder	Bipolar Affective Psychosis
Bipolar Spectrum Disorder	Manic Depressive Illness
Depression Bipolar	Bipolar Disorder, Mixed
Major Affective Disorder	Major Affective Disorder 1
Major Affective Disorder 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05232	GADL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GADL1	RGD	RGD:1565145
Macaca mulatta	GADL1	VGNC	VGNC:72796
Felis catus	GADL1	VGNC	VGNC:62433
Canis familiaris	GADL1	VGNC	VGNC:41073
Mus musculus	GADL1	MGD	MGI:1920998
Bos taurus	GADL1	VGNC	VGNC:29210

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