CDKL4 - cyclin dependent kinase like 4 Gene

Homo sapiens

Gene ID: 344387 | Gene type: protein coding

About CDKL4

This gene has 6 transcripts (splice variants), 88 orthologues and 26 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CDKL4 Products(3)

mRNA	Protein	Name
NM_001009565.2	NP_001009565.1	cyclin-dependent kinase-like 4 isoform 2
NM_001346911.1	NP_001333840.1	cyclin-dependent kinase-like 4 isoform 1
NM_001397900.1	NP_001384829.1	cyclin-dependent kinase-like 4 isoform 3

CDKL4 Protein Structure

Pkinase

0
100
200
300
379 a.a.

Protein Preferred Names

Protein Names

cyclin-dependent kinase-like 4

Related Diseases

Diseases

Alias

Gingival Fibromatosis

Hereditary Gingival Fibromatosis	Hereditary Gingival Hyperplasia
Autosomal Dominant Gingival Fibromatosis	Autosomal Dominant Gingival Hyperplasia
Fibromatosis, Gingival, Hereditary	Fibromatosis, Gingival

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02408	CDKL4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CDKL4	VGNC	VGNC:39066
Macaca mulatta	CDKL4	VGNC	VGNC:71031
Felis catus	CDKL4	VGNC	VGNC:60711
Rattus norvegicus	CDKL4	RGD	RGD:1583704
Mus musculus	CDKL4	MGD	MGI:3587025
Bos taurus	CDKL4	VGNC	VGNC:27141
Others	CDKL4	NCBI

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