1. Gene
  2. GNAT3 - G protein subunit alpha transducin 3 Gene

GNAT3 - G protein subunit alpha transducin 3 Gene

Homo sapiens

Also known as GDCA; HG1E

Gene ID: 346562 | Gene type: protein coding

About GNAT3

Cytogenetic location: 7q21.11 Genomic coordinates (GRCh38): 7:80,458,635-80,512,064 (from NCBI)

This gene has 1 transcript (splice variant), 238 orthologues and 15 paralogues. Low expression observed in reference dataset.

Summary

Sweet, bitter, and umami tastes are transmitted from taste receptors by a specific guanine nucleotide binding protein. The protein encoded by this gene is the alpha subunit of this heterotrimeric G protein, which is found not only in the oral epithelium but also in gut tissues. Variations in this gene have been linked to metabolic syndrome. [provided by RefSeq, Dec 2015]

GNAT3 Products(1)

mRNA Protein Name
NM_001102386.3 NP_001095856.1 guanine nucleotide-binding protein G(t) subunit alpha-3

GNAT3 Protein Structure

G-alpha

G-alpha: G-protein alpha subunit (7 - 343)

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  • 300
  • 354 a.a.
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(t) subunit alpha-3

guanine nucleotide binding protein, alpha transducing 3

Related Diseases

Diseases Alias
Invasive Malignant Thymoma

Infiltrating Thymoma

Thymoma Malignant Invasive

Invasive Thymoma And Thymic Carcinoma

Dental Caries

Dental Caries Extending Into Pulp

Dental Caries Of Smooth Surface

Dental Caries Pit And Fissure

Smooth Surface Dental Caries

Dental Decay

Carious Teeth

Dental Cavity

Saprodontia

Teeth Decayed

Tooth Caries

Tooth Decay

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta GNAT3 VGNC VGNC:108410
Rattus norvegicus GNAT3 RGD RGD:727817
Bos taurus GNAT3 VGNC VGNC:29456
Felis catus GNAT3 VGNC VGNC:80052
Mus musculus GNAT3 MGD MGI:3588268
Canis familiaris GNAT3 VGNC VGNC:41309