Vegfd - vascular endothelial growth factor D Gene

Rattus norvegicus

Also known as Figf; Vegf-d

Gene ID: 360457 | Gene type: protein coding

About Vegfd

Summary

Enables vascular endothelial growth factor receptor binding activity. Involved in several processes, including positive regulation of interleukin-6 production; regulation of vascular endothelial growth factor receptor signaling pathway; and response to interleukin-1. Predicted to be located in extracellular space. Orthologous to human VEGFD (vascular endothelial growth Factor D). [provided by Alliance of Genome Resources, Apr 2022]

Vegfd Products(1)

mRNA	Protein	Name
NM_031761.2	NP_113949.2	vascular endothelial growth factor D precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables vascular endothelial growth factor receptor binding	IMP IMP: Inferred from mutant phenotype	11683876	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of interleukin-6 production	IMP IMP: Inferred from mutant phenotype	17404025	RGD
involved in regulation of vascular endothelial growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	11683876	RGD
involved in response to hypoxia	IEP IEP: Inferred from expression pattern	17289933	RGD
involved in response to interleukin-1	IEP IEP: Inferred from expression pattern	17929249	RGD
involved in vascular endothelial growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	11683876	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

vascular endothelial growth factor D

c-fos-induced growth factor

Recombinant Vegfd Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73475	VEGF-DD Protein, Rat (HEK293, Fc)	O35251 (F94-R210)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15638	VEGFD Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9920A	Ramucirumab (anti-VEGFR)	Antagonist	99.36%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Vegfd	NCBI	NCBI:2277

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