2. Gene
  3. COL4A3 - Col4a3 collagen type IV alpha 3 chain Gene

COL4A3 - Col4a3 collagen type IV alpha 3 chain Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 363265 | Gene type: protein coding

About COL4A3

Summary

Predicted to enable Integrin binding activity. Predicted to be an extracellular matrix structural constituent. Involved in response to glucose. Predicted to be located in endoplasmic reticulum. Predicted to be part of collagen type IV trimer. Predicted to be active in basement membrane and extracellular space. Used to study glomerulonephritis. Human ortholog(s) of this gene implicated in Alport syndrome; autosomal dominant Alport syndrome; autosomal recessive Alport syndrome; benign familial hematuria; and end stage renal disease. Orthologous to human COL4A3 (collagen type IV alpha 3 chain). [provided by Alliance of Genome Resources, Apr 2022]

COL4A3 Products(1)

mRNA Protein Name
NM_001413988.1 NP_001400917.1 collagen alpha-3(IV) chain precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to glucose IEP
IEP: Inferred from expression pattern
12150963 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-3(IV) chain

collagen alpha-3(IV) chain-like

collagen, type IV, alpha 3 (Goodpasture antigen)

procollagen, type IV, alpha 3

Recombinant COL4A3 Proteins

Cat. No. Product Name Accession Purity
HY-P75683 COL4A3 Protein, Rat (HEK293, Fc) F1LRJ1 (G1426-H1670) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02985 COL4A3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens COL4A3 NCBI NCBI:1285