2. Gene
  3. Slc22a12 - solute carrier family 22 member 12 Gene

Slc22a12 - solute carrier family 22 member 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rst; URAT1; Slc22al2

Gene ID: 365398 | Gene type: protein coding

About Slc22a12

Primary_assembly 1: 203,845,048-203,853,555 reverse strand.mRatBN7.2:CM026974.1

This gene has 3 transcripts (splice variants), 475 orthologues, 24 paralogues and is associated with 8 phenotypes. Restricted expression toward (RPKM 74.6).

Summary

Predicted to enable PDZ domain binding activity and urate transmembrane transporter activity. Involved in cellular response to Insulin stimulus; urate salt excretion; and urate transport. Located in apical plasma membrane. Biomarker of diabetes mellitus. Orthologous to human SLC22A12 (solute carrier family 22 member 12). [provided by Alliance of Genome Resources, Apr 2022]

Slc22a12 Products(1)

mRNA Protein Name
NM_001034943.1 NP_001030115.1 solute carrier family 22 member 12

Slc22a12 Protein Structure

MFS_OAT

MFS_OAT: cd17374 (108 - 540)

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  • 578 a.a.
Protein Preferred Names Protein Names

solute carrier family 22 member 12

solute carrier family 22 (organic anion/cation transporter), member 12

solute carrier family 22 (organic anion/urate transporter), member 12

solute carrier family 22 (organic cation transporter)-like 2

urate anion exchanger 1

urate:anion antiporter SLC22A12

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13063 SLC22A12 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13064 Slc22a12 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13065 Slc22a12 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc22a12 NCBI NCBI:116085