2. Membrane Transporter/Ion Channel
  3. URAT1
  4. hURAT1 inhibitor 2

hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. hURAT1 inhibitor 2 also has a certain inhibitory effect on OATP1B1, with an IC50 value of 0.73 μM. hURAT1 inhibitor 2 can be used in the research of diseases related to abnormal uric acid metabolism, such as hyperuricemia and gout.

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hURAT1 inhibitor 2 Chemical Structure

hURAT1 inhibitor 2 Chemical Structure

CAS No. : 1402818-99-8

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hURAT1 inhibitor 2 Related Antibodies

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Description

hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. hURAT1 inhibitor 2 also has a certain inhibitory effect on OATP1B1, with an IC50 value of 0.73 μM. hURAT1 inhibitor 2 can be used in the research of diseases related to abnormal uric acid metabolism, such as hyperuricemia and gout[1].

Molecular Weight

442.07

Formula

C17H11Br2FO3
CAS No.
SMILES

O=C(C1=CC(Br)=C(O)C(Br)=C1)C2=C(CC)OC3=CC(F)=CC=C23
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hURAT1 inhibitor 2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hURAT1 inhibitor 21402818-99-8URAT1Urate transporter 1SLC22A12Inhibitorinhibitorinhibit

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