Lpar5 - lysophosphatidic acid receptor 5 Gene

Mus musculus

Also known as LPA5; GPR93; Gpr92; Gm1072

Gene ID: 381810 | Gene type: protein coding

About Lpar5

Chromosome 6: 125,044,883-125,059,435 forward strand.GRCm39:CM000999.3

This gene has 2 transcripts (splice variants), 252 orthologues, 1 paralogue and is associated with 11 phenotypes. Biased expression in small intestine adult (RPKM 19.8), duodenum adult (RPKM 18.6) and 7 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Acts upstream of or within behavioral response to pain and positive regulation of CREB transcription factor activity. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including future brain; gut; immune system; liver; and nervous system. Orthologous to human LPAR5 (lysophosphatidic acid receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Lpar5 Products(2)

mRNA	Protein	Name
NM_001163269.2	NP_001156741.2	lysophosphatidic acid receptor 5
NM_001163268.2	NP_001156740.2	lysophosphatidic acid receptor 5

Lpar5 Protein Structure

7tm_GPCRs

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

lysophosphatidic acid receptor 5

G protein-coupled receptor 92	LPA receptor 5
LPA-5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15706	H2L 5765834	Antagonist	98.36%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lpar5	NCBI	NCBI:57121

Name
Email *

	Sorry, but the email address you supplied was invalid.