1. Gene
  2. CLEC12B - C-type lectin domain family 12 member B Gene

CLEC12B - C-type lectin domain family 12 member B Gene

Homo sapiens

Also known as UNQ5782

Gene ID: 387837 | Gene type: protein coding

About CLEC12B

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,006,209-10,018,800 (from NCBI)

This gene has 5 transcripts (splice variants), 351 orthologues and 23 paralogues. Biased expression in testis (RPKM 8.0), skin (RPKM 1.6) and 1 other tissue.

Summary

Enables protein Phosphatase binding activity and signaling receptor inhibitor activity. Involved in natural killer cell inhibitory signaling pathway; negative regulation of natural killer cell mediated cytotoxicity; and negative regulation of signaling receptor activity. Located in external side of plasma membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

CLEC12B Products(5)

mRNA Protein Name
NM_001129998.3 NP_001123470.1 C-type lectin domain family 12 member B isoform 1
NM_001319241.1 NP_001306170.1 C-type lectin domain family 12 member B isoform 3
NM_001319242.1 NP_001306171.1 C-type lectin domain family 12 member B isoform 4
NM_001387138.1 NP_001374067.1 C-type lectin domain family 12 member B isoform 5
NM_205852.3 NP_995324.2 C-type lectin domain family 12 member B isoform 2

CLEC12B Protein Structure

Ly49

Ly49: Ly49-like protein, N-terminal region (38 - 157)

Lectin_C

Lectin_C: Lectin C-type domain (162 - 265)

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  • 276 a.a.
Protein Preferred Names Protein Names

C-type lectin domain family 12 member B

macrophage antigen h

Orthologs Information

Species Symbol Source ID
Mus musculus CLEC12B MGD MGI:1918433
Macaca mulatta CLEC12B VGNC VGNC:71378
Felis catus CLEC12B VGNC VGNC:60942
Rattus norvegicus CLEC12B RGD RGD:1560487
Canis familiaris CLEC12B VGNC VGNC:39326
Bos taurus CLEC12B VGNC VGNC:27424