ALKAL1 - ALK and LTK ligand 1 Gene

Homo sapiens

Also known as AUGA; AUGB; FAM150A; UNQ9433

Gene ID: 389658 | Gene type: protein coding

About ALKAL1

Cytogenetic location: 8q11.23 Genomic coordinates (GRCh38): 8:52,534,037-52,565,430 (from NCBI)

This gene has 2 transcripts (splice variants) and 161 orthologues. Biased expression in gall bladder (RPKM 1.3), thyroid (RPKM 1.1) and 7 other tissues.

Summary

Enables receptor signaling protein tyrosine kinase activator activity and receptor tyrosine kinase binding activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of ERK5 cascade; and positive regulation of neuron projection development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ALKAL1 Products(1)

mRNA	Protein	Name
NM_207413.4	NP_997296.1	ALK and LTK ligand 1 precursor

ALKAL1 Protein Structure

FAM150

0
100
129 a.a.

Protein Preferred Names

Protein Names

ALK and LTK ligand 1

AUG-beta

Recombinant ALKAL1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71584	ALKAL1 Protein, Human (His, B2M)	Q6UXT8 (R28-T129)	≥95%

Related Diseases

Diseases

Alias

Inflammatory Myofibroblastic Tumor

Inflammatory Fibrosarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00601	ALKAL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ALKAL1	VGNC	VGNC:83979
Mus musculus	ALKAL1	MGD	MGI:3645495
Canis familiaris	ALKAL1	VGNC	VGNC:49887
Felis catus	ALKAL1	VGNC	VGNC:105869
Rattus norvegicus	ALKAL1	RGD	RGD:1583530
Others	ALKAL1	NCBI

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