BSX - brain specific homeobox Gene

Homo sapiens

Also known as BSX1

Gene ID: 390259 | Gene type: protein coding

About BSX

Cytogenetic location: 11q24.1 Genomic coordinates (GRCh38): 11:122,977,570-122,981,834 (from NCBI)

This gene has 1 transcript (splice variant), 126 orthologues and 9 paralogues. Low expression observed in reference dataset.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including eating behavior; mammary gland involution; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

BSX Products(1)

mRNA	Protein	Name
NM_001098169.2	NP_001091639.1	brain-specific homeobox protein homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BSX Protein Structure

Homeobox

0
100
200
233 a.a.

Protein Preferred Names

Protein Names

brain-specific homeobox protein homolog

Related Diseases

Diseases

Alias

Jacobsen Syndrome

Chromosome 11q Deletion Syndrome	Partial 11q Monosomy Syndrome
Jacobsen Distal 11q Deletion Syndrome	JBS
11q Partial Monosomy Syndrome	Chromosome 11q Deletion
11q Deletion	11q Monosomy
Deletion 11q	Monosomy 11q
Partial Monosomy 11q	11q Deletion Disorder
11q Deletion Syndrome	11q Terminal Deletion Disorder
11q- Deletion Syndrome	11q23 Deletion Disorder
Jacobsen Thrombocytopenia	11q Terminal Deletion Syndrome
Del(11)(Q23.3)	Del(11)(Qter)
Distal Deletion 11q	Distal Monosomy 11q
Monosomy 11qter	Telomeric Deletion 11q
Paris-Trousseau Thrombocytopenia

Exocervical Carcinoma

Carcinoma Of Exocervix

Carcinoma Of The Exocervix

Autoimmune Glomerulonephritis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01650	BSX Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	BSX	RGD	RGD:1565120
Canis familiaris	BSX	VGNC	VGNC:38543
Macaca mulatta	BSX	VGNC	VGNC:107427
Felis catus	BSX	VGNC	VGNC:60192
Bos taurus	BSX	VGNC	VGNC:26582
Mus musculus	BSX	MGD	MGI:2669849

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