PATE4 - prostate and testis expressed 4 Gene

Homo sapiens

Also known as PATE-B

Gene ID: 399968 | Gene type: protein coding

About PATE4

This gene has 3 transcripts (splice variants), 30 orthologues and 4 paralogues. Low expression observed in reference dataset.

Summary

Enables acetylcholine receptor regulator activity. Involved in regulation of neurotransmitter receptor activity. Located in acrosomal vesicle and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

PATE4 Products(1)

mRNA	Protein	Name
NM_001144874.1	NP_001138346.1	prostate and testis expressed protein 4 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables acetylcholine receptor regulator activity	IDA IDA: Inferred from direct assay	18387948	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of neurotransmitter receptor activity	IDA IDA: Inferred from direct assay	18387948	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in acrosomal vesicle	IDA IDA: Inferred from direct assay	18387948	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	18387948	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

prostate and testis expressed protein 4

PATE-like protein B

Related Diseases

Diseases

Alias

Mal De Meleda

Meleda Disease	Keratosis Palmoplantaris Transgrediens Of Siemens
MDM	Transgrediens Palmoplantar Keratoderma Of Siemens
Acroerythrokeratoderma	Keratosis Palmoplantaris Transgradiens Of Siemens

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10082	PATE4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PATE4	MGD	MGI:1930790
Rattus norvegicus	PATE4	RGD	RGD:1311172

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