RGPD1 - RANBP2 like and GRIP domain containing 1 Gene

Homo sapiens

Also known as RGP1; RGPD2; RanBP2L2; ranBP2L6

Gene ID: 400966 | Gene type: protein coding

About RGPD1

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:86,913,324-87,013,976 (from NCBI)

This gene has 4 transcripts (splice variants), 21 orthologues and 10 paralogues. Broad expression in testis (RPKM 17.9), liver (RPKM 7.1) and 23 other tissues.

Summary

Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RGPD1 Products(3)

mRNA	Protein	Name
NM_001024457.4	NP_001019628.3	RANBP2-like and GRIP domain-containing protein 1 isoform 2
NM_001382344.1	NP_001369273.1	RANBP2-like and GRIP domain-containing protein 1 isoform 1
NM_001410915.1	NP_001397844.1	RANBP2-like and GRIP domain-containing protein 1 isoform 3

RGPD1 Protein Structure

TPR_1

Ran_BP1

GRIP

0
300
600
900
1200
1500
1748 a.a.

Protein Preferred Names

Protein Names

RANBP2-like and GRIP domain-containing protein 1

RANBP2-like and GRIP domain-containing protein 1/2

Related Diseases

Diseases

Alias

Myoclonic Cerebellar Dyssynergia

Dyssynergia Cerebellaris Myoclonica	Progressive Cerebellar Tremor
Dentate Cerebellar Ataxia	Dentatorubral Atrophy
Dyssynergia Cerebellaris Progressiva	Myoclonus And Ataxia
Primary Dentatum Atrophy	Progressive Myoclonus Ataxia
Ramsay Hunt Cerebellar Syndrome	Ramsay Hunt Syndrome Type 1

Charcot-Marie-Tooth Disease, Axonal, Type 2dd

CMT2DD	Charcot-Marie-Tooth Neuropathy, Type 2dd
Charcot-Marie-Tooth Disease Type 2dd	Atp1a1-Related Autosomal Dominant Charcot-Marie-Tooth Disease Type 2
Atp1a1-Related Cmt2	Autosomal Dominant Charcot-Marie-Tooth Disease Type 2dd
Charcot-Marie-Tooth Disease 2dd

Cerebrooculofacioskeletal Syndrome

Cerebro-Oculo-Facio-Skeletal Syndrome	Cofs Syndrome
Pena-Shokeir Syndrome Type 2	Pena Shokeir Syndrome Type 2

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11898	RGPD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RGPD1	MGD	MGI:894323

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