2. Gene
  3. ASB18 - ankyrin repeat and SOCS box containing 18 Gene

ASB18 - ankyrin repeat and SOCS box containing 18 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ASB-18

Gene ID: 401036 | Gene type: protein coding

About ASB18

This gene has 6 transcripts (splice variants), 109 orthologues and 7 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Feb 2017]

ASB18 Products(1)

mRNA Protein Name
NM_212556.4 NP_997721.2 ankyrin repeat and SOCS box protein 18

ASB18 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (124 - 212)

Ank

Ank: Ankyrin repeat (220 - 249)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (272 - 320)

SOCS_box

SOCS_box: SOCS box (421 - 459)

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  • 466 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 18

Related Diseases

Diseases Alias
Kleefstra Syndrome 1

9q Subtelomeric Deletion Syndrome

KLEFS1

Chromosome 9q34.3 Deletion Syndrome

9q- Syndrome

9q34 Deletion Syndrome

Kleefstra Syndrome Due To 9q34 Microdeletion

Kleefstra Syndrome

9q-Syndrome

9qstds

Kleefstra Syndrome Due To 9q Subtelomeric Deletion

Kleefstra Syndrome Due To Del(9)(Q34)

Kleefstra Syndrome Due To Monosomy 9q34

Chromosome 9q Subtelomeric Deletion Syndrome

Kleefstra Syndrome, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01066 ASB18 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ASB18 VGNC VGNC:80141
Canis familiaris ASB18 VGNC VGNC:38162
Mus musculus ASB18 MGD MGI:2655109
Bos taurus ASB18 VGNC VGNC:26195
Rattus norvegicus ASB18 RGD RGD:1310850