2. Gene
  3. LY6H - lymphocyte antigen 6 family member H Gene

LY6H - lymphocyte antigen 6 family member H Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NMLY6

Gene ID: 4062 | Gene type: protein coding

About LY6H

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:143,157,916-143,160,654 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 86 orthologues and 1 paralogue. Biased expression in brain (RPKM 15.6), stomach (RPKM 1.2) and 1 other tissue.

Summary

Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LY6H Products(3)

mRNA Protein Name
NM_001130478.2 NP_001123950.1 lymphocyte antigen 6H isoform b precursor
NM_001135655.2 NP_001129127.1 lymphocyte antigen 6H isoform b precursor
NM_002347.5 NP_002338.3 lymphocyte antigen 6H isoform a precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LY6H Protein Structure

UPAR_LY6

UPAR_LY6: u-PAR/Ly-6 domain (28 - 111)

  • 0
  • 100
  • 140 a.a.
Protein Preferred Names Protein Names

lymphocyte antigen 6H

ly-6H

Recombinant LY6H Proteins

Cat. No. Product Name Accession Purity
HY-P70217 Lymphocyte antigen 6H/LY6H Protein, Human (HEK293, His) O94772 (L26-G115) ≥95%

Related Diseases

Diseases Alias
Variola Minor

Alastrim

Cottonpox

Milkpox

Whitepox
Vertebral Artery Occlusion

Occlusion And Stenosis Of Vertebral Artery
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07901 LY6H Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LY6H VGNC VGNC:74462
Mus musculus LY6H MGD MGI:1346030
Felis catus LY6H VGNC VGNC:81669
Canis familiaris LY6H VGNC VGNC:51776
Rattus norvegicus LY6H RGD RGD:1311896
Bos taurus LY6H VGNC VGNC:31091
Others LY6H NCBI