LY75 - lymphocyte antigen 75 Gene

Homo sapiens

Also known as CD205; LY-75; CLEC13B; DEC-205; GP200-MR6

Gene ID: 4065 | Gene type: protein coding

About LY75

Cytogenetic location: 2q24.2 Genomic coordinates (GRCh38): 2:159,803,355-159,904,756 (from NCBI)

This gene has 4 transcripts (splice variants), 205 orthologues and 4 paralogues. Broad expression in lymph node (RPKM 17.2), appendix (RPKM 13.2) and 17 other tissues.

Summary

Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

LY75 Products(1)

mRNA	Protein	Name
NM_002349.4	NP_002340.2	lymphocyte antigen 75 precursor

LY75 Protein Structure

fn2

Lectin_C

0
300
600
900
1200
1500
1722 a.a.

Protein Preferred Names

Protein Names

lymphocyte antigen 75

C-type lectin domain family 13 member B

Recombinant LY75 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74203	DEC-205/CD205 Protein, Human (HEK293, His)	O60449-1/NP_002340.2 (A32-G1664)	≥95%

Related Diseases

Diseases

Alias

Pneumonic Plague

Primary Pneumonic Plague	Secondary Pneumonic Plague
Plague	Plague, Pneumonic
Plague Pneumonia	Plague Of Lung
Pulmonary Plague	Pneumonia Due To Yersinia Pestis

Membranous Nephropathy

Membranous Glomerulonephritis	Glomerulonephritis, Membranous
Idiopathic Membranous Nephropathy	Idiopathic Membranous Glomerulonephritis
MBNP	Membranous Nephropathy, Susceptibility To
Extramembranous Glomerulonephritis	Mgn
Membranous Gn	Primary Membranous Glomerulonephritis
Primary Membranous Nephropathy	Nephropathy Membranous

Adenoiditis

Chronic Adenoiditis

Lipid Pneumonia

Exogenous Lipoid Pneumonia	Lipoid Pneumonitis
Pneumonia, Lipid	Pneumonia Lipid
Lipoid Pneumonia

Lymphoma, Hodgkin, Classic

Hodgkin Lymphoma	Hodgkin Disease
Hodgkin'S Lymphoma	Hodgkins Lymphoma
Classic Hodgkin Lymphoma	CHL
Hodgkin Lymphoma, Susceptibility To	Hl
Hodgkin'S Sarcoma	Stage I Subdiaphragmatic Hodgkin Lymphoma
Stage Ii Subdiaphragmatic Hodgkin Lymphoma	Lymphoma, Hodgkin'S
Classic Hodgkin Disease	Hodgkin'S Disease
Lymphoma, Hodgkin, Susceptibility To	Hodgkin'S Disease Of Intrapelvic Lymph Nodes
Hodgkin'S Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb	Malignant Lymphogranuloma
Malignant Lymphogranulomatosis	Malignant Hodgkin Lymphoma
Classical Hodgkin Lymphoma, Type Not Specified

Plague

Yersiniosis	Yersinia Infections
Infection By Yersinia Pestis	Pasteurella Pestis Infection
Pestilential Fever	Yersinia Pestis Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07905	LY75 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LY75	RGD	RGD:1565962
Mus musculus	LY75	MGD	MGI:106662
Macaca fascicularis	LY75	NCBI	NCBI:102120600

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