ARSD - arylsulfatase D Gene

Homo sapiens

Also known as ASD

Gene ID: 414 | Gene type: protein coding

About ARSD

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:2,903,972-2,929,339 (from NCBI)

This gene has 7 transcripts (splice variants), 228 orthologues and 16 paralogues. Ubiquitous expression in kidney (RPKM 21.5), thyroid (RPKM 12.5) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]

ARSD Products(2)

mRNA	Protein	Name
NM_001669.4	NP_001660.2	arylsulfatase D isoform alpha precursor
NM_009589.5	NP_033667.2	arylsulfatase D isoform beta precursor

ARSD Protein Structure

Sulfatase

Sulfatase_C

0
100
200
300
400
500
593 a.a.

Protein Preferred Names

Protein Names

arylsulfatase D

testis tissue sperm-binding protein Li 39a

Related Diseases

Diseases

Alias

Chondrodysplasia Punctata, Tibia-Metacarpal Type

Chondrodysplasia Punctata, Mt Type

Chondrodysplasia Punctata, Tibial-Metacarpal Type

Pontiac Fever

Gastric Dilatation

Stomach Dilatation

Legionellosis

Legionella Infection	Pontiac Fever
Legionnaires' Disease	Infection By Legionella Pneumophilia
Legionella Pneumophila Infection

Legionnaire Disease

Legionnaires' Disease	Legionnaires Disease
Legionnaire Disease, Susceptibility To	Legionella
Legionella Pneumonia	Infection By Legionella Pneumophilia
Legionnaire'S Disease	Legionellosis
Legionaire Disease, Susceptibility To	Legionnaires Pneumonia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01036	ARSD Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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