2. Gene
  3. PSG8 - pregnancy specific beta-1-glycoprotein 8 Gene

PSG8 - pregnancy specific beta-1-glycoprotein 8 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens

Also known as PSG1

Gene ID: 440533 | Gene type: protein coding

About PSG8

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:42,752,686-42,765,678 (from NCBI)

This gene has 8 transcripts (splice variants), 630 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 46.5).

Summary

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

PSG8 Products(3)

mRNA Protein Name
NM_001130167.2 NP_001123639.1 pregnancy-specific beta-1-glycoprotein 8 isoform b precursor
NM_001130168.2 NP_001123640.1 pregnancy-specific beta-1-glycoprotein 8 isoform c
NM_182707.3 NP_874366.1 pregnancy-specific beta-1-glycoprotein 8 isoform a precursor

PSG8 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (36 - 127)

Ig_2

Ig_2: Immunoglobulin domain (148 - 234)

Ig_2

Ig_2: Immunoglobulin domain (253 - 328)

Ig_2

Ig_2: Immunoglobulin domain (335 - 413)

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  • 426 a.a.
Protein Preferred Names Protein Names

pregnancy-specific beta-1-glycoprotein 8

C1 alternate

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11287 PSG8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown