1. Gene
  2. TRIM67 - tripartite motif containing 67 Gene

TRIM67 - tripartite motif containing 67 Gene

Homo sapiens

Also known as TNL

Gene ID: 440730 | Gene type: protein coding

About TRIM67

Cytogenetic location: 1q42.2 Genomic coordinates (GRCh38): 1:231,162,058-231,221,565 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 80 paralogues. Biased expression in brain (RPKM 4.1) and adrenal (RPKM 0.2).

Summary

Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of protein localization. Predicted to act upstream of or within negative regulation of Ras protein signal transduction; positive regulation of neuron projection development; and positive regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

TRIM67 Products(3)

mRNA Protein Name
NM_001004342.5 NP_001004342.3 tripartite motif-containing protein 67 isoform 1
NM_001300889.3 NP_001287818.1 tripartite motif-containing protein 67 isoform 2
NM_001410937.1 NP_001397866.1 tripartite motif-containing protein 67 isoform 3

TRIM67 Protein Structure

zf-C3HC4

zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (7 - 35)

zf-B_box

zf-B_box: B-box zinc finger (301 - 340)

fn3

fn3: Fibronectin type III domain (526 - 597)

SPRY

SPRY: SPRY domain (649 - 767)

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  • 783 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 67

TRIM9-like protein TNL

Orthologs Information

Species Symbol Source ID
Mus musculus TRIM67 MGD MGI:3045323
Macaca mulatta TRIM67 VGNC VGNC:79915
Canis familiaris TRIM67 VGNC VGNC:47834
Bos taurus TRIM67 VGNC VGNC:55996
Rattus norvegicus TRIM67 RGD RGD:1560667