GALNTL6 - polypeptide N-acetylgalactosaminyltransferase like 6 Gene

Homo sapiens

Also known as GALNT17; GALNACT20; GalNAc-T6L

Gene ID: 442117 | Gene type: protein coding

About GALNTL6

Cytogenetic location: 4q34.1 Genomic coordinates (GRCh38): 4:171,813,404-173,041,559 (from NCBI)

This gene has 7 transcripts (splice variants), 202 orthologues and 19 paralogues. Low expression observed in reference dataset.

Summary

Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

GALNTL6 Products(1)

mRNA	Protein	Name
NM_001034845.3	NP_001030017.2	polypeptide N-acetylgalactosaminyltransferase-like 6

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables polypeptide N-acetylgalactosaminyltransferase activity	IDA IDA: Inferred from direct assay	22186971	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in protein O-linked glycosylation via threonine	IDA IDA: Inferred from direct assay	22186971	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GALNTL6 Protein Structure

Glycos_transf_2

Ricin_B_lectin

0
100
200
300
400
500
601 a.a.

Protein Preferred Names

Protein Names

polypeptide N-acetylgalactosaminyltransferase-like 6

GaNTase 17

Related Diseases

Diseases

Alias

Williams-Beuren Syndrome

Williams Syndrome	WBS
Wms	Deletion 7q11.23
Monosomy 7q11.23	Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb
Fanconi Schlesinger Syndrome	Beuren Syndrome
Elfin Facies Syndrome	Elfin Facies With Hypercalcemia
Hypercalcemia-Supravalvar Aortic Stenosis	Ws

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS05262	GALNTL6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	GALNTL6	MGD	MGI:1913581
Rattus norvegicus	GALNTL6	RGD	RGD:1564773
Canis familiaris	GALNTL6	VGNC	VGNC:59080
Macaca mulatta	GALNTL6	VGNC	VGNC:72813
Felis catus	GALNTL6	VGNC	VGNC:107336
Bos taurus	GALNTL6	VGNC	VGNC:29238

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