MT1H - metallothionein 1H Gene

Homo sapiens

Also known as MT1; MT-0; MT-1H; MT-IH

Gene ID: 4496 | Gene type: protein coding

About MT1H

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,669,814-56,671,129 (from NCBI)

This gene has 2 transcripts (splice variants), 210 orthologues and 11 paralogues. Biased expression in kidney (RPKM 179.8), small intestine (RPKM 88.9) and 6 other tissues.

Summary

Predicted to enable zinc ion binding activity. Involved in cellular response to cadmium ion and cellular response to zinc ion. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MT1H Products(1)

mRNA	Protein	Name
NM_005951.2	NP_005942.1	metallothionein-1H

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12646258	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to cadmium ion	IEP IEP: Inferred from expression pattern	16827180	GOA
involved in cellular response to zinc ion	IEP IEP: Inferred from expression pattern	8119276	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MT1H Protein Structure

Metallothio

0
61 a.a.

Protein Preferred Names

Protein Names

metallothionein-1H

metallothionein-0

Related Diseases

Diseases

Alias

Deficiency Anemia

Anemia	Deficiency Anemias
Anaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08740	MT1H Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MT1H	MGD	MGI:97171

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