MTCP1 - mature T cell proliferation 1 Gene

Homo sapiens

Also known as TCL1C; p8MTCP1; P13MTCP1

Gene ID: 4515 | Gene type: protein coding

About MTCP1

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:155,064,034-155,071,136 (from NCBI)

This gene has 4 transcripts (splice variants), 117 orthologues, 2 paralogues and is associated with 57 phenotypes. Ubiquitous expression in testis (RPKM 2.8), heart (RPKM 2.6) and 25 other tissues.

Summary

This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the upstream 13 kDa protein that is a member of the TCL1 family. This protein may be involved in leukemogenesis. [provided by RefSeq, Mar 2009]

MTCP1 Products(1)

mRNA	Protein	Name
NM_001018025.4	NP_001018025.1	protein p13 MTCP-1

MTCP1 Protein Structure

TCL1_MTCP1

0
100
107 a.a.

Protein Preferred Names

Protein Names

protein p13 MTCP-1

MTCP-1 type B1

Related Diseases

Diseases

Alias

Prolymphocytic Leukemia

Pll	Prolymphocytic Leukaemia
Leukemia Prolymphocytic	Leukemia, Prolymphocytic

T-Cell Prolymphocytic Leukemia

T Cell Prolymphocytic Leukemia	Prolymphocytic Leukemia, T-Cell Type
T-Pll	T-Cell Chronic Lymphocytic Leukemia
Lymphocytic Leukemia T-Cell Chronic	Doid:0081042
Leukemia, T-Cell, Chronic	Prolymphocytic Leukaemia Of T-Cell Type Without Mention Of Remission

Ataxia-Telangiectasia

Ataxia Telangiectasia	Louis-Bar Syndrome
AT	At1
Ataxia-Telangiectasia Syndrome	Ataxia - Telangiectasia Variant
Boder-Sedgwick Syndrome	Louis Bar Syndrome
Cerebello-Oculocutaneous Telangiectasia	Immunodeficiency With Ataxia Telangiectasia
A-T	Ataxia Telangiectasia Syndrome
Atm	Telangiectasia, Cerebello-Oculocutaneous
Ataxia-Telangiectasia Variant

Leukemia

Leukemias	Leukaemia, Unspecified, Without Mention Of Remission
Aleukemic Leukaemia	Chronic Leukaemia
Subacute Leukaemia	Leukaemia Disorder
Leukaemia Nos

Incontinentia Pigmenti

Bloch-Sulzberger Syndrome	IP
Incontinentia Pigmenti, Familial Male-Lethal Type	Incontinentia Pigmenti Syndrome
Bloch-Siemens Syndrome	Ip2
Incontinentia Pigmenti, Type Ii, Formerly	Ip2, Formerly
Incontinentia Pigmenti Type 2	Bloch-Siemens-Sulzberger Syndrome
Familial Incontinentia Pigmenti Male-Lethal Type	Familial Incontinentia Pigmenti Type Ii
Incontinentia Pigmenti, Type Ii	Bloch Sulzberger Syndrome
Incontinentia Pigmenti Achromians	Incontinentia Pigmenti Of Bloch-Sulzberger
Nevus Pigmentosus Systematicus

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia	Acute T Cell Leukemia
Precursor T Lymphoblastic Leukemia	Precursor T-Lymphoblastic Lymphoma/Leukemia
T Acute Lymphoblastic Leukemia	T-Cell Acute Lymphocytic Leukaemia
T-Cell Lymphoblastic Leukemia/Lymphoma	Leukemia T-Cell
Leukemia, T-Cell	Leukemia, Acute, Lymphoblastic, T-Cell
Leukemia, T-Cell Acute Lymphoblastic	Leukemia, Acute T-Cell
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Precursor T-Cell Lymphoblastic Lymphoma
Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08760	MTCP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MTCP1	RGD	RGD:1561352
Bos taurus	MTCP1	VGNC	VGNC:50220
Canis familiaris	MTCP1	VGNC	VGNC:43461
Mus musculus	MTCP1	MGD	MGI:102699
Macaca mulatta	MTCP1	VGNC	VGNC:74945
Felis catus	MTCP1	VGNC	VGNC:68337
Others	MTCP1	NCBI

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