2. Gene
  3. NDUFA7 - NADH:ubiquinone oxidoreductase subunit A7 Gene

NDUFA7 - NADH:ubiquinone oxidoreductase subunit A7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as B14.5a; CI-B14.5a

Gene ID: 4701 | Gene type: protein coding

About NDUFA7

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:8,308,595-8,321,375 (from NCBI)

This gene has 6 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in heart (RPKM 24.4), kidney (RPKM 16.8) and 25 other tissues.

Summary

This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the respiratory chain. [provided by RefSeq, Mar 2011]

NDUFA7 Products(1)

mRNA Protein Name
NM_005001.5 NP_004992.2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
28844695 GOA
part of respiratory chain complex I IDA
IDA: Inferred from direct assay
12611891 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NDUFA7 Protein Structure

CI-B14_5a

CI-B14_5a: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) (5 - 105)

  • 0
  • 100
  • 113 a.a.
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09133 NDUFA7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NDUFA7 MGD MGI:1913666
Rattus norvegicus NDUFA7 RGD RGD:1304597