2. Gene
  3. ACVR1 - activin A receptor type 1 Gene

ACVR1 - activin A receptor type 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 478757 | Gene type: protein coding

About ACVR1

Primary_assembly 36: 3,865,493-3,946,584 reverse strand.ROS_Cfam_1.0:CM025135.1

This gene has 2 transcripts (splice variants), 174 orthologues and 10 paralogues.

ACVR1 Products(4)

mRNA Protein Name
XM_038446785.1 XP_038302713.1 activin receptor type-1
XM_038446786.1 XP_038302714.1 activin receptor type-1
XM_038446783.1 XP_038302711.1 activin receptor type-1
XM_038446784.1 XP_038302712.1 activin receptor type-1

ACVR1 Protein Structure

Activin_recp

Activin_recp: pfam01064 (32 - 102)

TGF_beta_GS

TGF_beta_GS: pfam08515 (178 - 205)

STKc_ACVR1_ALK1

STKc_ACVR1_ALK1: cd14142 (201 - 498)

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  • 509 a.a.
Protein Preferred Names Protein Names

activin receptor type-1

Recombinant ACVR1 Proteins

Cat. No. Product Name Accession Purity
HY-P76714 ACVR1 Protein, Canine (HEK293, Fc) A0A811ZNW1/XP_549615.2 (M21-E123) ≥95%
HY-P76715 ACVR1 Protein, Canine (HEK293, His) A0A811ZNW1/XP_549615.2 (D23-E123) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-109179 Itacnosertib Inhibitor 99.06% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990022 Prafnosbart Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109179A Itacnosertib (hydrocholide) Inhibitor 99.43% Unkown
HY-RS00236 ACVR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00237 Acvr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00238 Acvr1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00239 ACVR1B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00240 Acvr1b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00241 Acvr1b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00242 ACVR1C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00243 Acvr1c Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00244 Acvr1c Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W064657 Momelotinib dihydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ACVR1 NCBI NCBI:90
Macaca fascicularis ACVR1 NCBI NCBI:102134051
Mus musculus ACVR1 NCBI NCBI:11477
Rattus norvegicus ACVR1 NCBI NCBI:79558
Macaca mulatta ACVR1 NCBI NCBI:697935