1. Gene
  2. ATP12A - ATPase H+/K+ transporting non-gastric alpha2 subunit Gene

ATP12A - ATPase H+/K+ transporting non-gastric alpha2 subunit Gene

Homo sapiens

Also known as HK; ATP1AL1; H-K-ATPase

Gene ID: 479 | Gene type: protein coding

About ATP12A

Cytogenetic location: 13q12.12 Genomic coordinates (GRCh38): 13:24,680,408-24,712,472 (from NCBI)

This gene has 2 transcripts (splice variants), 169 orthologues and 21 paralogues. Biased expression in esophagus (RPKM 7.0), kidney (RPKM 4.1) and 5 other tissues.

Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

ATP12A Products(2)

mRNA Protein Name
NM_001185085.2 NP_001172014.1 potassium-transporting ATPase alpha chain 2 isoform 1
NM_001676.7 NP_001667.4 potassium-transporting ATPase alpha chain 2 isoform 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables P-type potassium:proton transporter activity IDA
IDA: Inferred from direct assay
8853415 GOA
enables P-type sodium:potassium-exchanging transporter activity IDA
IDA: Inferred from direct assay
9774385 GOA
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
16914892 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ATP12A Protein Structure

Cation_ATPase_N

Cation_ATPase_N: Cation transporter/ATPase, N-terminus (59 - 126)

E1-E2_ATPase

E1-E2_ATPase: E1-E2 ATPase (151 - 381)

Hydrolase

Hydrolase: haloacid dehalogenase-like hydrolase (387 - 744)

Cation_ATPase_C

Cation_ATPase_C: Cation transporting ATPase, C-terminus (814 - 1024)

  • 0
  • 200
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  • 800
  • 1039 a.a.
Protein Preferred Names Protein Names

potassium-transporting ATPase alpha chain 2

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

Related Diseases

Diseases Alias
Peptic Esophagitis

Reflux Esophagitis

Peptic Reflux Disease

Reflux Oesophagitis

Esophagitis, Peptic

Gastro-Esophageal Reflux Disease With Esophagitis

Hernia, Hiatus

Hiatal Hernia

Hiatus Hernia

Diaphragmatic - Hiatus -Hernia

Hernia, Hiatal

Active Peptic Ulcer Disease

Gi Bleeding

Active Peptic Ulcer

Gastrointestinal Hemorrhage

Chronic Laryngitis
Volvulus Of Midgut

Volvulus

Intestinal Volvulus

Intestinal Malrotation, Familial

Familial Intestinal Malrotation

Twist Of Intestine, Bowel, Or Colon

Dieulafoy Lesion

Dieulafoy'S Lesion

Dieulafoy Lesion Of Intestine

Dieulafoy Lesion Of Stomach And Duodenum

Dieulafoy Disease

Exulceratio Simplex Dieulafoy

Dieulafoy'S Vascular Malformation

Lymphocytic Colitis

Colitis, Lymphocytic

Gastroduodenitis
Duodenal Obstruction
Aspiration Pneumonitis

Chemical Pneumonitis

Mendelson'S Syndrome

Aspiration Pneumonia

Pneumonitis Due To Fumes And/Or Vapors

Toxic Pneumonitis

Mendelson'S Syndrome Resulting From A Procedure

Mendelson Syndrome Resulting From A Procedure

Pulmonary Acid Aspiration Syndrome

Pneumonitis Due To Inhalation Of Gastric Secretions

Mendelson Syndrome Due To Anaesthesia During Labour And Delivery

Inhalation Of Stomach Contents Or Secretions, Nos Due To Anaesthesia During Labour And Delivery

Gastroduodenal Crohn'S Disease

Upper Gi Crohn'S Disease

Lymphocytic Gastritis
Gastrojejunal Ulcer

Acute Gastrojejunal Ulcer With Hemorrhage

Acute Gastrojejunal Ulcer With Hemorrhage And Obstruction

Acute Gastrojejunal Ulcer With Hemorrhage And Perforation

Acute Gastrojejunal Ulcer With Hemorrhage And Perforation, With Obstruction

Acute Gastrojejunal Ulcer With Hemorrhage, With Perforation And With Obstruction

Acute Gastrojejunal Ulcer With Perforation

Acute Gastrojejunal Ulcer With Perforation And Obstruction

Acute Gastrojejunal Ulcer With Perforation, With Obstruction

Acute Gastrojejunal Ulcer Without Hemorrhage And Without Perforation

Acute Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction

Acute Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction

Acute Gastrojejunal Ulcer, With Hemorrhage, With Obstruction

Chronic Gastrojejunal Ulcer Without Hemorrhage And Without Perforation

Chronic Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction

Chronic Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction

Marginal Ulcer

Dyskinesia Of Esophagus

Esophageal Motility Disorders

Dyskinesia Of Oesophagus

Esophageal Dysmotility

Esophageal Motility Disorder

Oesophageal Dysmotility

Oesophageal Motor Disorder

Esophageal Spasm

Superior Mesenteric Artery Syndrome

Wilkie Syndrome

Wilkie'S Syndrome

Arteriomesenteric Duodenal Compression Syndrome

Cast Syndrome

Vascular Compression Of The Duodenum

Smas

Arteriomesenteric Compression Of Duodenojejunal Flexure

Blind Loop Syndrome

Bacterial Overgrowth Syndrome

Gastric Dilatation

Stomach Dilatation

Chronic Intestinal Vascular Insufficiency

Chronic Mesenteric Ischemia

Cmi - Chronic Mesenteric Ischaemia

Internal Hemorrhoid

Internal Hemorrhoids

Peptic Ulcer Perforation

Perforated Peptic Ulcer

Acute Peptic Ulcer With Perforation

Peptic Ulcer With Perforation

Median Arcuate Ligament Syndrome

Celiac Artery Compression Syndrome

Dunbar Syndrome

Mals

Harjola-Marable Syndrome

Marable'S Syndrome

Celiac Axis Syndrome

Granulomatous Gastritis
Microscopic Colitis

Colitis, Microscopic

Gastric Hemangioma

Hemangioma Of Stomach

Toxic Megacolon

Megacolon, Toxic

Toxic Dilatation Of Colon

Toxic Functional Megacolon

Esophageal Candidiasis

Candidiasis Of The Esophagus

Candida Esophagitis

Candidal Esophagitis

Esophageal Moniliasis

Esophageal Thrush

Acquired Gastric Outlet Stenosis

Adult Hypertrophic Pyloric Stenosis

Acquired Hypertrophic Pyloric Stenosis

Rumination Disorder

Rumination Syndrome

Psychogenic Rumination

Rumination Disorders

Bacterial Esophagitis
Esophagitis, Eosinophilic, 1

Eosinophilic Esophagitis

EOE1

Esophagitis, Eosinophilic

Ee

Hemorrhoid

Hemorrhoids

Hemorrhoidal Disease

Rectal Diseases

Piles

Unspecified Haemorrhoids Without Complication

Angiodysplasia Of Intestine
Ischemic Colitis

Colitis, Ischemic

Irreversible Ischaemic Colitis

Fungal Esophagitis
Pancreatic Vasoactive Intestinal Peptide Producing Tumor

Pancreatic Vasoactive Intestinal Peptide Producing Tumour

Pancreatic Vip Producing Tumor

Pancreatic Vip Producing Tumour

Pancreatic Vipoma

Acquired Laryngomalacia
Clostridium Difficile Colitis

Pseudomembranous Colitis

Colitis Pseudomembranous

Enterocolitis, Pseudomembranous

Pseudomembranous Enterocolitis

Clostridium Difficile Infection

Necrotizing Gastritis
Aspiration Pneumonia

Pneumonia, Aspiration

Pneumonia Aspiration

Aspiration Pneumonitis

Lingual Goiter
Benign Shuddering Attacks

Shuddering Attacks

Beta-Lactam Allergy
Persistent Moderate Asthma
Collagenous Colitis

Colitis, Collagenous

Microscopic Colitis, Collagenous Type

Scalp Dermatosis

Scalp Dermatoses

Dermatosis Of Scalp

Autoimmune Gastritis
Duodenitis

Hemorrhagic Duodenitis

Acute Enteritis Of The Mouse Intestinal Tract

Nonspecific Duodenitis

Inflammation Of Duodenum

Dodecadactylitis

Duodenal Inflammation

Peptic Duodenitis

Gastric Antral Vascular Ectasia

Watermelon Stomach

Gave

Functional Gastric Disease
Bile Reflux
Peptic Ulcer Disease

Peptic Ulcer

Acute Peptic Ulcer With Hemorrhage

Acute Peptic Ulcer With Hemorrhage And Perforation

Acute Peptic Ulcer Without Hemorrhage And Without Perforation

Duodenum Disease

Duodenal Diseases

Duodenal Disease

Duodenum Disorder

Gastric Lymphoma

Familial Primary Gastric Lymphoma

Lymphoma Of The Stomach

Primary Gastric Lymphoma

Mediastinitis
Laryngitis

Acute Laryngitis

Esophageal Varix

Esophageal Varices

Bleeding Esophageal Varices

Bleeding Oesophageal Varices

Esophageal Varices In Disease Classified Elsewhere, With Bleeding

Esophageal Varices With Bleeding

Esophageal Varices With Bleeding In Disease Ec

Esophageal Varices Without Bleeding

Esophageal Varices Without Mention Of Bleeding

Gastritis, Familial Giant Hypertrophic

Menetrier Disease

Gastric Mucosal Hypertrophy

Giant Hypertrophic Gastritis

Hypertrophic Gastropathy

Gastritis, Hypertrophic

Familial Giant Hypertrophic Gastritis

Giant Rugal Hypertrophy Of Stomach

Hypertrophic Gastritis

Gastroenteropathy, Protein Losing

Giant Hypertrophic Gastropathy

Giant Hypertrophy Of The Gastric Mucosa

Hypoproteinemic Hypertrophic Gastropathy

Menetrier'S Disease

Giant Hypertrophic Hypersecretory Gastritis

Polyposis, Skin Pigmentation, Alopecia, And Fingernail Changes

Cronkhite-Canada Syndrome

Gastric Cronkhite Canada Polyposis

Cronkhite-Canada Disease

Polyposis Skin Pigmentation Alopecia Fingernail Changes

Gastrointestinal Polyposis-Ectodermal Changes Syndrome

Gastrointestinal Polyposis-Skin Pigmentation-Alopecia-Fingernail Changes Syndrome

Polyposis, Gastrointestinal, With Ectodermal Changes

Afferent Loop Syndrome

Afferent Limb Syndrome

Esophageal Diverticulosis

Diverticulosis, Esophageal

Cough Variant Asthma
Eosinophilic Gastritis

Eosinophilic Enteropathy

Drug Allergy

Allergy Drug

Drug Allergies

Angiodysplasia

Angiodysplasia Of Colon

Angiodysplasia Of Stomach And Duodenum With Hemorrhage

Angiodysplasia Of Large Intestine

Telangiectasia Of Colon

Vascular Ectasia Of Colon

Av - [Angiodysplasia Malformation Of Colon]

Colon Angiodysplasia

Colonic Angiodysplasia

Vascular Ectasia Of Large Intestine

Esophageal Disease

Esophageal Diseases

Esophageal Ulcer

Esophageal Disorder

Ulcer Of Esophagus

Viral Esophagitis
Vitamin Metabolic Disorder
Eosinophilic Gastroenteritis

Eosinophilic Enteritis

Ege

Eosinophilic Gastroenterocolitis

Eosinophilic Esophagitis

Eosinophilic Gastritis

Eosinophilic Gastroenteropathy

Gastroenteritis, Eosinophilic

Eosinophilic Enteropathy

Displacement Of Cardia Through Esophageal Hiatus

Congenital Hiatus Hernia

Congenital Hiatal Hernia

Congenital Displacement Of Cardia Through Oesophageal Hiatus

Congenital Hiatus Oesophageal Hernia

Congenital Paraoesophageal Hernia

Congenital Sliding Hiatal Hernia

Congenital Oesophageal Hiatal Hernia

Pernicious Anemia

Anemia, Pernicious

Anemia Pernicious

Pernicious Anaemia

Addison'S Anaemia

Biermer'S Anaemia

Biermer'S Anemia

Acquired Pernicious Anemia

Addison-Biermer Anemia

Addisonian Anemia

Biermer Anemia

Biermer'S Disease

Juvenile Onset Pernicious Anemia

Biermer Disease

Biermer-Addison Disease

Paralytic Ileus

Adynamic Ileus

Paralytic Ileus Of Bowel

Ileus Nos

Paralysis Of Bowel

Paralysis Of Intestine

Adynamic Intestinal Obstruction

Paralytic Intestinal Ileus

Zollinger-Ellison Syndrome

Gastrinoma

Pancreatic Ulcerogenic Tumor Syndrome

Z E Syndrome

Zes

Ze - [Zollinger-Ellison] Syndrome

Benzylpenicillin Allergy

Benzyl Penicillin Allergy

Penicillin G Allergy

Duodenogastric Reflux
Gastric Gastrinoma

Gastric G-Cell Gastrin Producing Tumor

Gastric Gastrin-Producing Neuroendocrine Tumor

Megaesophagus

Esophageal Achalasia

Squamous Papillomatosis
Vitamin B12 Deficiency

Cobalamin Deficiency

Hypocobalaminemia

Vitamin B 12 Deficiency

Cyanocobalamin Deficiency

Deficiency Of Vitamin B12

Pneumatosis Cystoides Intestinalis
Vein Disease

Disorder Of Vein

Penicillin Allergy

Allergy To Penicillin

Interstitial Nephritis

Nephritis, Interstitial

Renal Tubulo-Interstitial Disease

Nephritis Interstitial

Nephritis, Tubulointerstitial

Lactose Intolerance

Lactose Malabsorption

Lm - Lactose Malabsorption

Alactasia

Dairy Product Intolerance

Hypolactasia

Milk Sugar Intolerance

Cow Milk Enteropathy

Intolerance Or Malabsorption Of Lactose

Lm - [Lactose Malabsorption]

Milk Intolerance

Acute Laryngitis

Acute Laryngitis Nos

Laryngeal Inflammation

Laryngitis Nos

Larynx Inflammation

Functional Diarrhea

Functional Diarrhoea

Laryngeal Tuberculosis

Tuberculosis, Laryngeal

Pylorospasm
Postgastrectomy Syndrome

Postgastrectomy Syndromes

Postgastric Surgery Syndrome

Esophagus Adenocarcinoma

Esophageal Adenocarcinoma

Oesophageal Adenocarcinoma

Adenocarcinoma Of Esophagus

Adenocarcinoma Of The Esophagus

Endosteal Hyperostosis, Autosomal Dominant

Osteosclerosis

Worth Syndrome

Osteosclerosis, Autosomal Dominant

Hyperostosis, Endosteal

Endosteal Hyperostosis, Worth Type

Worth Disease

Autosomal Dominant Endosteal Hyperostosis

Autosomal Dominant Osteosclerosis, Worth Type

Hyperostosis Corticalis Generalisata, Benign Form Of Worth, With Torus Palatinus

Autosomal Dominant Osteosclerosis

Benign Form Of Worth Hyperostosis Corticalis Generalisata With Torus Platinus

Worth'S Syndrome

Worth Type Autosomal Dominant Osteosclerosis

Hyperostosis Corticalis Generalisata, Benign Form Of Worth With Torus Palatinus

Osteosclerosis, Autosomal Dominant, Worth Type

WENHY

Endosteal Hyperostosis Autosomal Dominant

Hyperostosis Corticalis Generalisata Benign Form Of Worth With Torus Palatinus

Osteosclerosis Autosomal Dominant

Acquired Osteosclerosis

Pancreatic Gastrinoma

Pancreatic G-Cell Tumor

Duodenal Gastrinoma

Duodenal G-Cell Gastrin Producing Tumor

Gastrinoma Of Duodenum

Malignant Duodenal Gastrinoma

Duodenal Gastrin-Producing Neuroendocrine Tumor

Fungal Gastritis
Diclofenac Allergy

Voltaren Allergy

Barrett'S Adenocarcinoma

Barrett Adenocarcinoma

Adenocarcinoma Arising In Barrett'S Mucosa

Tracheomalacia

Congenital Tracheomalacia

Congenital Major Airway Collapse

Tracheomalacia, Congenital

Type 1 Tracheomalacia

Biliary Dyskinesia

Sphincter Of Oddi Dysfunction

Tracheal Disease

Tracheal Diseases

Tracheal Anomaly

Tracheal Disorders

Chronic Duodenal Ileus
Meckel Diverticulum

Meckel'S Diverticulum

Persistent Vitelline Duct

Intestinal Perforation

Perforation Of Intestine

Emphysematous Cholecystitis

Gaseous Pericholecystitis

Microinvasive Gastric Cancer

Early Gastric Cancer

Surface Gastric Cancer

Cascade Stomach

Hourglass Stricture Or Stenosis Of Stomach

Hourglass Contraction Of Stomach

Hourglass Stenosis Of Stomach

Hourglass Stricture Of Stomach

Common Bile Duct Disease

Common Bile Duct Diseases

Atrophic Glossitis

Atrophy Of Tongue Papillae

Glossitis, Hunter'S

Hunter'S Glossitis

Smooth Atrophic Tongue

Hunter Glossitis

Central Papillary Atrophy Of The Tongue

Atrophic Gastritis

Gastritis, Atrophic

Gastric Atrophy

Gastritis Atrophic

Splenic Artery Aneurysm

Aneurysm Of Splenic Artery

Cecal Disease

Cecal Diseases

Disorder Of Cecum

Bacterial Gastritis
Myopathy, X-Linked, With Excessive Autophagy

X-Linked Myopathy With Excessive Autophagy

Xmea

MEAX

Vacuolar Myopathy

Diverticulitis
Cervix Erosion

Erosion Of Cervix

Uterine Cervical Erosion

Esophagus Melanoma

Melanoma Of Esophagus

Melanoma Of Oesophagus

Oesophagus Melanoma

Esophageal Melanoma

Bacterial Pneumonia

Gram-Negative Pneumonia

Pneumonia Due To Other Gram-Negative Bacteria

Pneumonia Bacterial

Pneumonia, Bacterial

Acute Bacillus Pneumonia

Acute Bacterial Pneumonia

Bacillus Double Pneumonia

Bacillus Pneumonia

Bacteria Pneumonia

Bacterial Double Pneumonia

Bacterial Lobar Pneumonia

Bacterial Purulent Pneumonia

Bronchopneumonia Due To Bacteria Other Than S. Pneumoniae And H. Influenzae

Intestinal Obstruction

Inspissated Milk Syndrome

Milk Curd Syndrome

Rectal Disease

Rectal Diseases

Rectal Disorders

Laryngomalacia

Congenital Laryngomalacia

Congenital Laryngeal Stridor

Laryngomalacia Congenital

Floppy Epiglottis

Pyuria

Pus Cells In Urine

Glossitis

Inflammation Of Tongue

Tongue Inflammation

Glazed Tongue

Barrett Esophagus

Barrett'S Esophagus

Barrett Esophagus/Esophageal Adenocarcinoma

Barrett Metaplasia

Barrett'S Ulcer Of Esophagus

Ulcerative Esophagitis

Barrett'S Esophagus With Esophagitis

Barrett'S Oesophagus

Barretts Syndrome

Barrett Syndrome

BE

Peptic Ulcer Of Esophagus

Adenocarcinoma Of Esophagus

Choledocholithiasis
Central Nervous System Origin Vertigo

Vertigo Of Central Origin

Vertigo

Central Vestibular Vertigo

Osmotic Diarrhea
Giardiasis

Beaver Feaver

Infection By Giardia Lamblia

Lambliasis

Giardia Lamblia Dysentery

Giardial Diarrhoea

Lamblia Dysentery

Giardia Duodenalis Dysentery

Giardia Intestinalis Dysentery

Deficiency Anemia

Anemia

Deficiency Anemias

Anaemia

X-Linked Chondrodysplasia Punctata 1

Chondrodysplasia Punctata 1, X-Linked

Arylsulfatase E Deficiency

Chondrodystrophia Calcificans Congenita

Cdpx1

X-Linked Recessive Chondrodysplasia Punctata 1

Brachytelephalangic Chondrodysplasia Punctata

Atrial Septal Defect 8

ASD8

Atrial Heart Septal Defect 8

Septal Defect, Atrial, Type 8

Somatoform Disorder

Physiological Malfunction Arising From Mental Factor

Psychosomatic Disorder

Psychophysiologic Disorders

Hepatic Coma

Hepatic Encephalopathy

Hepatocerebral Intoxication

Cefuroxime Allergy

Cephuroxime Allergy

Zinacef Allergy

Chlorhexidine Allergy
Esophageal Leukoplakia

Leukoplakia Of Esophagus

Achalasia

Cardiospasm

Achalasia Of Cardia

Esophageal Achalasia

Hypertensive Lower Esophageal Sphincter

Idiopathic Achalasia

Achalasia Cardia

Idiopathic Achalasia Of Esophagus

Primary Achalasia

Achalasia Of Esophagus

Lack Of Reflex Relaxation Of Lower Oesophageal Sphincter

Aperistalsis Of The Oesophagus

Achalasia Of Oesophagus

Oesophageal Achalasia

Achalasia Nos

Cardia Spasm

Cardia Achalasia

Oesophageal Cardiospasm

Oesophagus Achalasia

Reflex Cardiospasm

Cardia Cancer

Ca Cardia - Stomach

Malignant Neoplasm Of Cardia Of Stomach

Dysentery

Infectious Diarrhea

Abdominal Tuberculosis
Angular Cheilitis

Cheilosis

Angular Cheilosis

Angular Stomatitis

Commissural Cheilitis

Gastric Neuroendocrine Neoplasm

Gastric Neuroendocrine Tumor

Neuroendocrine Tumor Of The Stomach

Neuroendocrine Tumor Of Stomach

Gnet

Gastric Net

Net Of Stomach

Marginal Zone B-Cell Lymphoma

Marginal Zone Lymphoma

Mzl

Mucosa-Associated Lymphoid Tissue Lymphoma

Lymphoma, Mucosa-Associated Lymphoid Type

Malt Lymphoma

Gastric Lymphoma, Primary

Lymphoma, Malt, Somatic

Mucosa-Associated Lymphoid Tissue Lymphoma

Extranodal Marginal Zone B-Cell Lymphoma

MALTOMA

Marginal Zone B-Cell Lymphoma

Mucosa-Associated Lymphatic Tissue Lymphoma

Primary Gastric Lymphoma

Gastric Lymphoma

Familial Primary Gastric Lymphoma

Hepatic Vascular Disease

Vascular Disorder Of Liver

Anus Disease

Anal Fissure

Ulcer Of Anus

Anus Diseases

Anal Disease

Anal Fissure And Fistula

Anal Ulcer

Fissure In Ano

Nontraumatic Tear Of Anus

Solitary Anal Ulcer

Abnormality Of The Anus

Anal Disorders

Ulcer Of Anus And Rectum

Solitary Ulcer Of Anus

Stercoral Ulcer Of Anus

Acute Cholangitis
Gastroesophageal Reflux

Gastroesophageal Reflux Disease

Gerd

GER

Gastroesophageal Reflux, Pediatric

Acid Reflux

Gastresophageal Reflux

Gastro-Esophageal Reflux

Gerd - Gastro-Esophageal Reflux Disease

Apnea, Obstructive Sleep

Obstructive Sleep Apnea Syndrome

Obstructive Sleep Apnea

Sleep Apnea, Obstructive

Osa

Osas

Sleep Apnea/Hypopnea Syndrome

Sahs

Upper Airway Resistance Sleep Apnea Syndrome

Apnea, Obstructive

Obstructive Apnea

Osahs

Sleep Apnea Hypopnea Syndrome

Sleep Apnea Syndrome, Obstructive

Sleep Apnea Obstructive

Sleep Apnea Syndromes

Obstructive Sleep Apnoea Syndrome

Obstructive Sleep Apnoea, Adult

Osa - [Obstructive Sleep Apnoea]

Obstructive Sleep Apnoea, Paediatric

Obstructive Sleep Apnoea Hypopnoea Syndrome

Osa Syndrome

Sleep Apnoea Nos

[Sas] - Sleep Apnoea Syndrome

Sleep Apnoea Syndrome

[Osahs] - Obstructive Sleep Apnoea-Hypopnea Syndrome

[Sahs] - Sleep Apnoea-Hypopnea Syndrome

Nutritional Deficiency Disease

Malnutrition

Nutritional Disorder

Nutritional Deficiency

Nutrition

Deficiency Diseases

Carbamoyl-Phosphate Synthase I Deficiency Disease

Nutrition Disorders

Paine Syndrome

Pain Disorder

Pain

Microcephaly With Spastic Diplegia

Pain Syndrome

Primary Thrombocytopenia
Prostatic Hypertrophy

Benign Prostatic Hypertrophy

Prostatic Hyperplasia

Barbiturate Abuse
Celiac Disease 1

Celiac Disease

Coeliac Disease

Celiac Sprue

Celiac Disease, Susceptibility To

Gluten-Sensitive Enteropathy

Nontropical Sprue

Sprue

CELIAC1

Celiac Disease, Susceptibility To, 1

Celiac Sprue 1

Celiac Sprue, Susceptibility To, 1

Gluten-Sensitive Enteropathy 1

Gluten-Sensitive Enteropathy, Susceptibility To, 1

Idiopathic Steatorrhea

Cœliac Disease

Gluten Intolerance

Gluten-Induced Enteropathy

Gluten Enteropathy

Celiac Disease, Susceptibility To, Type 1

Childhood Celiac Disease

Coeliac Rickets

Gee Disease

Gee-Herter Disease

Heubner-Herter Disease

Idiopathic Steatorrhoea

Thaysen'S Disease

Herter Gee Syndrome

Hypopigmentation Of Eyelid
Megaloblastic Anemia

Imerslund-Grasbeck Syndrome

Igs

Defect Of Enterocyte Intrinsic Factor Receptor

Enterocyte Cobalamin Malabsorption

Familial Megaloblastic Anemia

Megaloblastic Anemia 1

Selective Cobalamin Malabsorption With Proteinuria

Imerslund-Gräsbeck Syndrome

Anemia, Megaloblastic

Grasbeck-Imerslund Syndrome

Megaloblastic Anaemia

Mga1 Norwegian Type

Recessive Hereditary Megaloblastic Anaemia 1

Recessive Hereditary Megaloblastic Anemia 1

Rh-Mga1

Gräsbeck-Imerslund Disease

Pernicious Anemia, Juvenile, Due To Selective Intestinal Malabsorption Of Vitamin B12, With Proteinuria

Juvenile Pernicious Anemia With Proteinuria Due To Selective Intestinal Malabsorption Of Vitamin B12

Anemia Megaloblastic

Megaloblastic Anemia Due To Inborn Errors Of Metabolism

3-@Methylglutaconic Aciduria, Type I

Megacolon

Dilatation Of Colon

Opportunistic Mycosis

Opportunistic Mycoses

Opportunistic Systemic Mycoses

Cardiomyopathy, Dilated, 1gg

Dilated Cardiomyopathy 1gg

CMD1GG

Cardiomyopathy, Dilated 1gg

Cardiomyopathy, Dilated, Type 1gg

Esophageal Tuberculosis

Tuberculosis Of Esophagus

Pelvic Varices

Varix Of Pelvis

Pelvic Varicose Vein

Fungal Infectious Disease

Mycoses

Mycosis

Urinary Tract Infection

Urinary Tract Infections

Uti

Urinary Tract Infection Nos

Uti - [Urinary Tract Infection]

Uti Nos - [Urinary Tract Infection Nos]

Urosepsis Nos

E Coli Uti

E Coli Urinary Tract Infection

Escherichia Coli Uti

Autosomal Recessive Cutis Laxa Type Ii Classic Type

Arcl2, Classic Type

Arcl2, Debre Type

Autosomal Recessive Cutis Laxa Type 2, Classic Type

Autosomal Recessive Cutis Laxa Type 2, Debre Type

Aggressive Systemic Mastocytosis

Asm

Lymphadenopathic Mastocytosis With Eosinophilia

Autoimmune Disease Of Gastrointestinal Tract
Exanthem

Exanthema

Rash

Rashes

Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus

Alcohol Use Disorder

Alcohol Abuse

Alcoholism

Ethanol Abuse

Alcohol Addiction

Alcohol Dependence

Alcoholic Intoxication, Chronic

Alcohol-Related Disorders

Constipation
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Heart Conduction Disease

Conduction Disorder Of The Heart

Heart Rhythm Disease

Esophageal Atresia

Tracheoesophageal Fistula

Congenital Atresia Of Esophagus

Congenital Imperforate Esophagus

Imperforate Esophagus

Oesophageal Atresia

Te Fistula

Tef

Tracheoesophageal Fistula With Or Without Esophageal Atresia

Severe Cutaneous Adverse Reaction

Stevens-Johnson Syndrome

Toxic Epidermal Necrolysis

Drug-Induced Stevens Johnson Syndrome

Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum

Susceptibility To Severe Cutaneous Adverse Reaction

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

Lyell'S Syndrome

Lyell Syndrome

Severe Cutaneous Adverse Reaction, Susceptibility To

Hypersensitivity Syndrome, Carbamazepine-Induced, Susceptibility To

Hypersensitivity Syndrome, Carbamazepine-Induced

Stevens-Johnson Syndrome, Susceptibility To

Toxic Epidermal Necrolysis, Susceptibility To

Sjs/Ten

Susceptibility To Severe Cutaneous Adverse Reaction Ity To

Mycoplasma-Induced Stevens Johnson Syndrome

Dermatostomatitis, Stevens Johnson Type

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Spectrum

Sjs-Ten

Toxic Epidermolysis

SJS

Dermatostomatitis Stevens Johnson Type

Ten

Sjs/Ten - [Stevens-Johnson Syndrome And Toxic Epidermal Necrolysis]

Ten - [Toxic Epidermal Necrolysis]

Multiple Endocrine Neoplasia, Type I

Multiple Endocrine Neoplasia Type 1

MEN1

Wermer Syndrome

Multiple Endocrine Neoplasia 1

Multiple Endocrine Neoplasia, Type 1

Men I

Endocrine Adenomatosis, Multiple

Mea I

Men Type I

Wermer'S Syndrome

Men1 Syndrome

Multiple Endocrine Adenomatosis

Endocrine Adenomatosis Multiple

Men 1

Familial Multiple Endocrine Neoplasia Type I

Neoplasia, Endocrine, Multiple, Type 1

Multiple Endocrine Neoplasia

Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration

Esophageal Neuroendocrine Tumor

Esophageal Neuroendocrine Tumour

Neuroendocrine Tumor Of Esophagus

Neuroendocrine Tumour Of Oesophagus

Beach Ear

Acute Swimmer'S Ear

Acute Bacterial Inflammation Of External Ear

Acute Otitis Externa, Diffuse

Acute Swimmers' Ear

Tank Ear

Outlet Dysfunction Constipation
Diaphragmatic Hernia, Congenital

Congenital Diaphragmatic Hernia

Diaphragmatic Hernia

Cdh

Congenital Diaphragmatic Defect

Hernia, Diaphragmatic

Dih

Hernia, Congenital Diaphragmatic

Hcd

Diaphragmatic Defect, Congenital

Diaphragm, Unilateral Agenesis Of

Hemidiaphragm, Agenesis Of

Diaphragmatic Hernia 1

Agenesis Of Hemidiaphragm

Unilateral Agenesis Of Diaphragm

Hernia Diaphragmatic

Hernia Diaphragmatic Congenital

Hernia, Diaphragmatic, Type 1

Hiatus Hernia

Oesophageal Hiatus Hernia

Paraoesophageal Hernia

Sliding Hiatus Hernia

Congenital Diaphragm Hernia

Congenital Diaphragm Defect With Hernia

Gross Congenital Diaphragm Defect

Bilirubin Metabolic Disorder

Hyperbilirubinemia

Hereditary Hyperbilirubinemia

Hyperbilirubinemia, Hereditary

Hyperbilirubinaemia

Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To

Skin Disease

Skin Diseases

Genodermatosis

Abnormality Of The Skin

Skin Diseases, Genetic

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus ATP12A VGNC VGNC:26276
Mus musculus ATP12A MGD MGI:1926943
Rattus norvegicus ATP12A RGD RGD:620569
Felis catus ATP12A VGNC VGNC:60014
Canis familiaris ATP12A VGNC VGNC:38240
Macaca mulatta ATP12A VGNC VGNC:70067