2. Gene
  3. SNU13 - small nuclear ribonucleoprotein 13 Gene

SNU13 - small nuclear ribonucleoprotein 13 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FA1; FA-1; NHPX; 15.5K; OTK27; SSFA1; NHP2L1; SPAG12; SNRNP15-5

Gene ID: 4809 | Gene type: protein coding

About SNU13

Cytogenetic location: 22q13.2 Genomic coordinates (GRCh38): 22:41,673,933-41,690,480 (from NCBI)

This gene has 12 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in brain (RPKM 32.6), adrenal (RPKM 31.2) and 25 other tissues.

Summary

Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

SNU13 Products(2)

mRNA Protein Name
NM_001003796.2 NP_001003796.1 NHP2-like protein 1
NM_005008.4 NP_004999.1 NHP2-like protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATPase binding IPI
IPI: Inferred from physical interaction
17636026 GOA
enables U3 snoRNA binding IDA
IDA: Inferred from direct assay
11081632 GOA
enables U4 snRNA binding IDA
IDA: Inferred from direct assay
11081632 GOA
enables U4atac snRNA binding IDA
IDA: Inferred from direct assay
16857676 GOA
enables box C/D sno(s)RNA binding IDA
IDA: Inferred from direct assay
11081632 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
10593953 GOA
contributes to snoRNA binding IDA
IDA: Inferred from direct assay
17636026 GOA
Biological Process GO Annotation Evidence Reference Source
involved in mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
28781166 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence Reference Source
part of U2-type precatalytic spliceosome IDA
IDA: Inferred from direct assay
28781166 GOA
part of U4/U6 x U5 tri-snRNP complex IDA
IDA: Inferred from direct assay
26912367 GOA
part of U4/U6 x U5 tri-snRNP complex IPI
IPI: Inferred from physical interaction
30975767 GOA
part of U4atac snRNP IDA
IDA: Inferred from direct assay
21784869 GOA
part of box C/D methylation guide snoRNP complex IDA
IDA: Inferred from direct assay
11081632 GOA
located in dense fibrillar component IDA
IDA: Inferred from direct assay
10593953 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
10593953 GOA
located in nucleus IDA
IDA: Inferred from direct assay
28781166 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
17636026 GOA
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNU13 Protein Structure

Ribosomal_L7Ae

Ribosomal_L7Ae: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (21 - 111)

  • 0
  • 100
  • 128 a.a.
Protein Preferred Names Protein Names

NHP2-like protein 1

NHP2 non-histone chromosome protein 2-like 1

Recombinant SNU13 Proteins

Cat. No. Product Name Accession Purity
HY-P71161 NHP2L1 Protein, Human (His) P55769 (M1-V128) ≥95%

Related Diseases

Diseases Alias
Microcephalic Osteodysplastic Primordial Dwarfism, Type I

Taybi-Linder Syndrome

Brachymelic Primordial Dwarfism

Cephaloskeletal Dysplasia

Low-Birth-Weight Dwarfism With Skeletal Dysplasia

Microcephalic Osteodysplastic Primordial Dwarfism Type I

Osteodysplastic Primordial Dwarfism Type I

Primordial Microcephalic Dwarfism, Crachami Type

Osteodysplastic Primordial Dwarfism, Type 1

MOPD1

Mopd I

Mopd

Osteodysplastic Primordial Dwarfism, Type I

Tals

Microcephalic Osteodysplastic Primordial Dwarfism Type 1

Mopd 1

Microcephalic Osteodysplastic Primordial Dwarfism Types 1 And 3

Microcephalic Osteodysplastic Primordial Dwarfism Types I And Iii

Mopd Types I And Iii

Microcephalic Osteodysplastic Primordial Dwarfism, Taybi-Linder Type

Primordial Microcephalic Dwarfism Crachami Type

Dwarfism, Primordial, Osteodysplastic, Microcephalic, Type 1
Dyskeratosis Congenita

Dyskeratosis Congenita Autosomal Dominant

Dc

Dkc

Zinsser-Engman-Cole Syndrome

Dyskeratosis Congenita, Autosomal Dominant

Autosomal Dominant Dyskeratosis Congenita

Dkca

Dyskeratosis Congenita Scoggins Type

Zinsser-Cole-Engman Syndrome

X-Linked Dyskeratosis Congenita

Hoyeraal-Hreidarsson Syndrome
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13518 SNU13 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SNU13 VGNC VGNC:98450
Mus musculus SNU13 MGD MGI:893586
Rattus norvegicus SNU13 RGD RGD:1303103
Bos taurus SNU13 VGNC VGNC:35087
Others SNU13 NCBI