TAS2R1 - taste 2 receptor member 1 Gene

Homo sapiens

Also known as T2R1; TRB7

Gene ID: 50834 | Gene type: protein coding

About TAS2R1

Cytogenetic location: 5p15.31-p15.2 Genomic coordinates (GRCh38): 5:9,627,347-9,903,876 (from NCBI)

This gene has 3 transcripts (splice variants), 162 orthologues and 23 paralogues.

Summary

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by Taste Receptor cells of the tongue and palate epithelia. This intronless Taste Receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter Taste Receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]

TAS2R1 Products(2)

mRNA	Protein	Name
NM_001386348.1	NP_001373277.1	taste receptor type 2 member 1 isoform 2
NM_019599.3	NP_062545.1	taste receptor type 2 member 1 isoform 1

TAS2R1 Protein Structure

TAS2R

0
100
200
299 a.a.

Protein Preferred Names

Protein Names

taste receptor type 2 member 1

taste receptor, family B, member 7

Related Diseases

Diseases

Alias

Cri-Du-Chat Syndrome

5p Deletion Syndrome	5p Partial Monosomy Syndrome
Monosomy 5p	Cat Cry Syndrome
Chromosome 5p Deletion Syndrome	Cri Du Chat Syndrome
5p- Syndrome	5p Minus Syndrome
Chromosome 5p- Syndrome	Chromosome 5 Short Arm Deletion Syndrome
Chromosome 5p Deletion	Deletion 5p
Cri Du Chat	5p Partial Deletion Syndrome
Partial Deletion Of Short Arm Of Chromosome 5 Syndrome

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14215	TAS2R1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TAS2R1	RGD	RGD:620733
Canis familiaris	TAS2R1	VGNC	VGNC:47114
Felis catus	TAS2R1	VGNC	VGNC:65959
Macaca mulatta	TAS2R1	VGNC	VGNC:110429
Mus musculus	TAS2R1	MGD	MGI:2681253
Bos taurus	TAS2R1	VGNC	VGNC:35609

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