HEBP1 - heme binding protein 1 Gene

Homo sapiens

Also known as HBP; HEBP

Gene ID: 50865 | Gene type: protein coding

About HEBP1

Cytogenetic location: 12p13.1 Genomic coordinates (GRCh38): 12:12,974,870-13,000,265 (from NCBI)

This gene has 5 transcripts (splice variants), 148 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 103.7), small intestine (RPKM 72.8) and 25 other tissues.

Summary

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 Amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]

HEBP1 Products(1)

mRNA	Protein	Name
NM_015987.5	NP_057071.2	heme-binding protein 1

HEBP1 Protein Structure

SOUL

0
100
189 a.a.

Protein Preferred Names

Protein Names

heme-binding protein 1

p22HBP

Related Diseases

Diseases

Alias

Pica Disease

Pica

Proliferative Vasculopathy And Hydranencephaly-Hydrocephaly Syndrome

Fowler Syndrome	Encephaloclastic Proliferative Vasculopathy
Hydrocephaly/Hydranencephaly Due To Cerebral Vasculopathy	PVHH
Epv	Cerebral Proliferative Glomeruloid Vasculopathy
Hydranencephaly, Fowler Type	Proliferative Vasculopathy And Hydranencephaly/Hydrocephaly
Fowler'S Syndrome	Fowler Christmas Chapple Syndrome
Fowler Vasculopathy	Polycystic Ovaries Urethral Sphincter Dysfunction
Voiding Dysfunction And Polycystic Ovaries	Fowler Vasculopaty
Hydranencephaly Fowler Type	Pgv
Polycystic Ovaries-Urethral Sphincter Dysfunction Syndrome

Folate Malabsorption, Hereditary

Hereditary Folate Malabsorption	Congenital Defect Of Folate Absorption
Congenital Folate Malabsorption	Folic Acid Transport Defect
HFM

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06104	HEBP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	HEBP1	RGD	RGD:1304581
Mus musculus	HEBP1	MGD	MGI:1333880
Macaca mulatta	HEBP1	VGNC	VGNC:73184
Felis catus	HEBP1	VGNC	VGNC:62781
Canis familiaris	HEBP1	VGNC	VGNC:41639
Others	HEBP1	NCBI

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