2. Gene
  3. RAB14 - RAB14, member RAS oncogene family Gene

RAB14 - RAB14, member RAS oncogene family Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FBP; RAB-14

Gene ID: 51552 | Gene type: protein coding

About RAB14

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:121,178,133-121,201,869 (from NCBI)

This gene has 8 transcripts (splice variants), 205 orthologues, 68 paralogues and is associated with 1 phenotype. Ubiquitous expression in brain (RPKM 33.7), lung (RPKM 31.9) and 25 other tissues.

Summary

RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009]

RAB14 Products(1)

mRNA Protein Name
NM_016322.4 NP_057406.2 ras-related protein Rab-14

RAB14 Protein Structure

Ras

Ras: Ras family (13 - 173)

  • 0
  • 100
  • 200
  • 215 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-14

F protein-binding protein 1

Related Diseases

Diseases Alias
Gapo Syndrome

GAPOS

Growth Retardation, Alopecia, Pseudoanodontia, And Optic Atrophy

Growth Delay-Alopecia-Pseudoanodontia-Optic Atrophy Syndrome

Growth Retardation, Alopecia, Pseudoanodontia And Optic Atrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11523 RAB14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RAB14 VGNC VGNC:97581
Bos taurus RAB14 VGNC VGNC:33622
Canis familiaris RAB14 VGNC VGNC:45254
Mus musculus RAB14 MGD MGI:1915615
Rattus norvegicus RAB14 RGD RGD:620881