PHAX - phosphorylated adaptor for RNA export Gene

Homo sapiens

Also known as RNUXA

Gene ID: 51808 | Gene type: protein coding

About PHAX

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:126,600,947-126,627,252 (from NCBI)

This gene has 5 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in brain (RPKM 11.7), endometrium (RPKM 7.4) and 25 other tissues.

Summary

Enables mRNA cap binding complex binding activity. Involved in RNA stabilization. Located in centrosome and nucleoplasm. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

PHAX Products(1)

mRNA	Protein	Name
NM_032177.4	NP_115553.2	phosphorylated adapter RNA export protein

PHAX Protein Structure

RNA_GG_bind

0
100
200
300
394 a.a.

Protein Preferred Names

Protein Names

phosphorylated adapter RNA export protein

RNA U small nuclear RNA export adapter protein

Related Diseases

Diseases

Alias

Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant

ADLD	Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy
Leukodystrophy, Adult-Onset, Autosomal Dominant	Adult-Onset Autosomal Dominant Leukodystrophy
Autosomal Dominant Leukodystrophy With Autonomic Disease	Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy
Multiple Sclerosis-Like Disorder	Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly
Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease	Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type
Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms	Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy
Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset	Pelizaeus-Merzbacher Disease Autosomal Dominant
Pelizaeus-Merzbacher Disease Late-Onset Type	Adult Onset Autosomal Dominant Leukodystrophy

Retinitis Pigmentosa 57

RP57	Pde6g-Related Retinitis Pigmentosa
Retinitis Pigmentosa, Type 57

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10406	PHAX Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PHAX	MGD	MGI:1891839
Macaca mulatta	PHAX	VGNC	VGNC:97805
Felis catus	PHAX	VGNC	VGNC:64131
Rattus norvegicus	PHAX	RGD	RGD:708448
Bos taurus	PHAX	VGNC	VGNC:32807
Canis familiaris	PHAX	VGNC	VGNC:51915

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