2. Gene
  3. GALNT7 - polypeptide N-acetylgalactosaminyltransferase 7 Gene

GALNT7 - polypeptide N-acetylgalactosaminyltransferase 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GalNAcT7; GALNAC-T7

Gene ID: 51809 | Gene type: protein coding

About GALNT7

Cytogenetic location: 4q34.1 Genomic coordinates (GRCh38): 4:173,168,811-173,323,967 (from NCBI)

This gene has 7 transcripts (splice variants), 217 orthologues and 19 paralogues. Broad expression in stomach (RPKM 19.2), colon (RPKM 18.8) and 23 other tissues.

Summary

This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The Enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This Enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this Enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated Peptides. This protein may function as a follow-up Enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008]

GALNT7 Products(4)

mRNA Protein Name
NM_001375599.1 NP_001362528.1 N-acetylgalactosaminyltransferase 7 isoform 5
NM_001375600.1 NP_001362529.1 N-acetylgalactosaminyltransferase 7 isoform 2
NM_001375601.1 NP_001362530.1 N-acetylgalactosaminyltransferase 7 isoform 3
NM_017423.3 NP_059119.2 N-acetylgalactosaminyltransferase 7 isoform 1

GALNT7 Protein Structure

Glycos_transf_2

Glycos_transf_2: Glycosyl transferase family 2 (210 - 362)

Glyco_transf_7C

Glyco_transf_7C: N-terminal domain of galactosyltransferase (381 - 443)

Ricin_B_lectin

Ricin_B_lectin: Ricin-type beta-trefoil lectin domain (534 - 649)

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  • 657 a.a.
Protein Preferred Names Protein Names

N-acetylgalactosaminyltransferase 7

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7

Recombinant GALNT7 Proteins

Cat. No. Product Name Accession Purity
HY-P70867 GALNT7 Protein, Human (HEK293, His) Q86SF2 (P30-V657) ≥95%

Related Diseases

Diseases Alias
Scrotum Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Scrotum

Scrotal Squamous Cell Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05260 GALNT7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GALNT7 VGNC VGNC:72876
Felis catus GALNT7 VGNC VGNC:107055
Rattus norvegicus GALNT7 RGD RGD:620362
Mus musculus GALNT7 MGD MGI:1349449
Bos taurus GALNT7 VGNC VGNC:29235
Others GALNT7 NCBI