Avpr1a - arginine vasopressin receptor 1A Gene

Mus musculus

Also known as V1a; AVPR; V1aR; Avpr1

Gene ID: 54140 | Gene type: protein coding

About Avpr1a

Chromosome 10: 122,284,404-122,289,357 forward strand.GRCm39:CM001003.3

This gene has 1 transcript (splice variant), 264 orthologues, 16 paralogues and is associated with 20 phenotypes. Biased expression in liver adult (RPKM 15.9), bladder adult (RPKM 11.1) and 13 other tissues.

Summary

This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues [provided by RefSeq, Jul 2008]

Avpr1a Products(1)

mRNA	Protein	Name
NM_016847.2	NP_058543.2	vasopressin V1a receptor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of blood pressure	IMP IMP: Inferred from mutant phenotype	26531127	MGI
acts upstream of or within regulation of systemic arterial blood pressure by vasopressin	IGI IGI: Inferred from genetic interaction	12486173	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Avpr1a Protein Structure

7tmA_V1aR

DUF1856

0
100
200
300
400
423 a.a.

Protein Preferred Names

Protein Names

vasopressin V1a receptor

AVPR V1a	V1a arginine vasopressin receptor
antidiuretic hormone receptor 1a	vascular/hepatic-type arginine vasopressin receptor

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0049A	Argipressin diacetate		/	Unkown

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P4990	Pro8-Oxytocin	Activator	/	Unkown
HY-P4990A	Pro8-Oxytocin TFA	Activator	/	Unkown
HY-RS01281	AVPR1A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS01282	Avpr1a Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS01283	Avpr1a Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Avpr1a	NCBI	NCBI:552

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