2. Gene
  3. ZDHHC13 - zinc finger DHHC-type palmitoyltransferase 13 Gene

ZDHHC13 - zinc finger DHHC-type palmitoyltransferase 13 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HIP14L; HIP3RP

Gene ID: 54503 | Gene type: protein coding

About ZDHHC13

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:19,117,104-19,176,415 (from NCBI)

This gene has 8 transcripts (splice variants), 216 orthologues and 2 paralogues. Ubiquitous expression in esophagus (RPKM 18.5), urinary bladder (RPKM 11.0) and 24 other tissues.

Summary

Predicted to enable magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC13 Products(2)

mRNA Protein Name
NM_001001483.3 NP_001001483.1 palmitoyltransferase ZDHHC13 isoform 2
NM_019028.3 NP_061901.2 palmitoyltransferase ZDHHC13 isoform 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
16647879 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZDHHC13 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (86 - 171)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (201 - 271)

DHHC

DHHC: DHHC palmitoyltransferase (389 - 557)

  • 0
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  • 500
  • 622 a.a.
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC13

DHHC-13

Related Diseases

Diseases Alias
Huntington Disease

Huntington'S Disease

Huntington Chorea

Huntington'S Chorea

HD

Huntington Chronic Progressive Hereditary Chorea

Juvenile Huntington Disease

Chronic Progressive Chorea

Chronic Progressive Hereditary Chorea

Hc - [Huntington Chorea]

Hereditary Chorea

Progressive Hereditary Chorea
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16013 ZDHHC13 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ZDHHC13 VGNC VGNC:79138
Felis catus ZDHHC13 VGNC VGNC:67202
Canis familiaris ZDHHC13 VGNC VGNC:48579
Rattus norvegicus ZDHHC13 RGD RGD:1309736
Mus musculus ZDHHC13 MGD MGI:1919227
Bos taurus ZDHHC13 VGNC VGNC:37128