2. Gene
  3. Nphs1 - nephrosis 1, nephrin Gene

Nphs1 - nephrosis 1, nephrin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as nephrin; NephrinB

Gene ID: 54631 | Gene type: protein coding

About Nphs1

Summary

Predicted to enable cell adhesion molecule binding activity; cytoskeletal protein binding activity; and protein domain specific binding activity. Involved in myoblast fusion; regulation of excretion; and skeletal muscle tissue development. Acts upstream of or within JNK cascade; cell adhesion; and positive regulation of actin filament polymerization. Located in cell projection; focal adhesion; and plasma membrane. Is expressed in central nervous system and metanephros. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 1. Orthologous to human NPHS1 (NPHS1 adhesion molecule, nephrin). [provided by Alliance of Genome Resources, Apr 2022]

Nphs1 Products(1)

mRNA Protein Name
NM_019459.2 NP_062332.2 nephrin precursor
Protein Preferred Names Protein Names

nephrin

nephrin 1

nephrosis 1 homolog, nephrin

renal glomerulus-specific cell adhesion receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16221 Nphs1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09486 NPHS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nphs1 NCBI NCBI:4868