ST7L - suppression of tumorigenicity 7 like Gene

Homo sapiens

Also known as ST7R; STLR; FAM4B

Gene ID: 54879 | Gene type: protein coding

About ST7L

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,517,803-112,619,684 (from NCBI)

This gene has 28 transcripts (splice variants), 210 orthologues and 1 paralogue. Broad expression in testis (RPKM 6.6), skin (RPKM 3.2) and 24 other tissues.

Summary

This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]

ST7L Products(5)

mRNA	Protein	Name
NM_001308264.2	NP_001295193.1	suppressor of tumorigenicity 7 protein-like isoform 7
NM_017744.5	NP_060214.2	suppressor of tumorigenicity 7 protein-like isoform 1
NM_138727.4	NP_620055.1	suppressor of tumorigenicity 7 protein-like isoform 2
NM_138728.3	NP_620056.1	suppressor of tumorigenicity 7 protein-like isoform 3
NM_138729.4	NP_620057.1	suppressor of tumorigenicity 7 protein-like isoform 4

ST7L Protein Structure

ST7

0
100
200
300
400
500
575 a.a.

Protein Preferred Names

Protein Names

suppressor of tumorigenicity 7 protein-like

ST7-related protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13855	ST7L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ST7L	RGD	RGD:1359336
Bos taurus	ST7L	VGNC	VGNC:35343
Macaca mulatta	ST7L	VGNC	VGNC:77954
Felis catus	ST7L	VGNC	VGNC:65735
Canis familiaris	ST7L	VGNC	VGNC:46863
Mus musculus	ST7L	MGD	MGI:2386964

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