1. Gene
  2. ELOVL2 - ELOVL fatty acid elongase 2 Gene

ELOVL2 - ELOVL fatty acid elongase 2 Gene

Homo sapiens

Also known as SSC2

Gene ID: 54898 | Gene type: protein coding

About ELOVL2

Cytogenetic location: 6p24.2 Genomic coordinates (GRCh38): 6:10,980,759-11,044,305 (from NCBI)

This gene has 1 transcript (splice variant), 156 orthologues and 6 paralogues. Biased expression in placenta (RPKM 12.7), liver (RPKM 10.4) and 6 other tissues.

Summary

Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid and very long-chain fatty acid biosynthetic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

ELOVL2 Products(1)

mRNA Protein Name
NM_017770.4 NP_060240.3 elongation of very long chain fatty acids protein 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables fatty acid elongase activity EXP
EXP: Inferred from Experiment
10970790 GOA
enables fatty acid elongase activity IDA
IDA: Inferred from direct assay
12371743 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
20937905 GOA
Biological Process GO Annotation Evidence Reference Source
involved in fatty acid elongation, polyunsaturated fatty acid IDA
IDA: Inferred from direct assay
12371743 GOA
involved in very long-chain fatty acid biosynthetic process IDA
IDA: Inferred from direct assay
12371743 GOA
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
20937905 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELOVL2 Protein Structure

ELO

ELO: GNS1/SUR4 family (31 - 264)

  • 0
  • 100
  • 200
  • 296 a.a.
Protein Preferred Names Protein Names

elongation of very long chain fatty acids protein 2

3-keto acyl-CoA synthase ELOVL2

Related Diseases

Diseases Alias
Retinitis Pigmentosa 37

RP37

Retinitis Pigmentosa-37

Retinitis Pigmentosa, Type 37

Inguinal Hernia

Hernia Inguinal

Hernia, Inguinal

Inguinal Hernias

Bubonocele

Indirect Inguinal Hernia

Direct Inguinal Hernia

Oblique Inguinal Hernia

Scrotal Hernia

Ih - [Inguinal Hernia]

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ELOVL2 RGD RGD:1308605
Bos taurus ELOVL2 VGNC VGNC:28448
Macaca mulatta ELOVL2 VGNC VGNC:72045
Mus musculus ELOVL2 MGD MGI:1858960
Canis familiaris ELOVL2 VGNC VGNC:40320
Felis catus ELOVL2 VGNC VGNC:61823