2. Gene
  3. NOL8 - nucleolar protein 8 Gene

NOL8 - nucleolar protein 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NOP132; C9orf34; bA62C3.3; bA62C3.4

Gene ID: 55035 | Gene type: protein coding

About NOL8

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:92,297,358-92,325,350 (from NCBI)

This gene has 29 transcripts (splice variants) and 225 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), appendix (RPKM 6.7) and 25 other tissues.

Summary

NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]).[supplied by OMIM, Mar 2008]

NOL8 Products(3)

mRNA Protein Name
NM_001256394.2 NP_001243323.1 nucleolar protein 8 isoform b
NM_001330722.2 NP_001317651.1 nucleolar protein 8 isoform c
NM_017948.6 NP_060418.4 nucleolar protein 8 isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11073942 GOA
Biological Process GO Annotation Evidence Reference Source
involved in protein localization to nucleolus IMP
IMP: Inferred from mutant phenotype
16963496 GOA
involved in rRNA processing IMP
IMP: Inferred from mutant phenotype
16963496 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleolus IDA
IDA: Inferred from direct assay
14660641 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NOL8 Protein Structure

(10 - 82)

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  • 1167 a.a.
Protein Preferred Names Protein Names

nucleolar protein 8

nucleolar protein Nop132

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09418 NOL8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NOL8 VGNC VGNC:106844
Rattus norvegicus NOL8 RGD RGD:1309551
Mus musculus NOL8 MGD MGI:1918180
Macaca mulatta NOL8 VGNC VGNC:75237
Felis catus NOL8 VGNC VGNC:63853
Canis familiaris NOL8 VGNC VGNC:54850