SLC25A36 - solute carrier family 25 member 36 Gene

Homo sapiens

Also known as PNC2

Gene ID: 55186 | Gene type: protein coding

About SLC25A36

Cytogenetic location: 3q23 Genomic coordinates (GRCh38): 3:140,941,836-140,980,995 (from NCBI)

This gene has 16 transcripts (splice variants), 298 orthologues and 49 paralogues. Ubiquitous expression in bone marrow (RPKM 19.4), endometrium (RPKM 15.5) and 24 other tissues.

Summary

Enables pyrimidine nucleotide transmembrane transporter activity. Involved in mitochondrial genome maintenance; pyrimidine nucleotide transport; and regulation of mitochondrial membrane potential. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

SLC25A36 Products(2)

mRNA	Protein	Name
NM_001104647.3	NP_001098117.1	solute carrier family 25 member 36 isoform a
NM_018155.3	NP_060625.2	solute carrier family 25 member 36 isoform b

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables pyrimidine nucleotide transmembrane transporter activity	IDA IDA: Inferred from direct assay	25320081	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in mitochondrial genome maintenance	IDA IDA: Inferred from direct assay	25320081	GOA
involved in mitochondrion organization	IDA IDA: Inferred from direct assay	25320081	GOA
involved in pyrimidine nucleotide transport	IDA IDA: Inferred from direct assay	25320081	GOA
involved in regulation of mitochondrial membrane potential	IDA IDA: Inferred from direct assay	25320081	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	25320081	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC25A36 Protein Structure

Mito_carr

0
100
200
311 a.a.

Protein Preferred Names

Protein Names

solute carrier family 25 member 36

epididymis secretory sperm binding protein

Related Diseases

Diseases

Alias

Verrucous Papilloma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS13118	SLC25A36 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SLC25A36	VGNC	VGNC:84079
Felis catus	SLC25A36	VGNC	VGNC:102844
Mus musculus	SLC25A36	MGD	MGI:1924909
Bos taurus	SLC25A36	VGNC	VGNC:34762
Rattus norvegicus	SLC25A36	RGD	RGD:1591928
Canis familiaris	SLC25A36	VGNC	VGNC:46310

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