ZNF407 - zinc finger protein 407 Gene

Homo sapiens

Also known as SIMHA

Gene ID: 55628 | Gene type: protein coding

About ZNF407

Cytogenetic location: 18q22.3 Genomic coordinates (GRCh38): 18:74,597,870-75,065,671 (from NCBI)

This gene has 8 transcripts (splice variants), 200 orthologues, 51 paralogues and is associated with 2 phenotypes. Ubiquitous expression in testis (RPKM 1.7), ovary (RPKM 1.3) and 25 other tissues.

Summary

This gene encodes a zinc finger protein whose exact function is not known. It may be involved in transcriptional regulation. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

ZNF407 Products(4)

mRNA	Protein	Name
NM_001146189.1	NP_001139661.1	zinc finger protein 407 isoform 2
NM_001146190.1	NP_001139662.1	zinc finger protein 407 isoform 3
NM_001384475.1	NP_001371404.1	zinc finger protein 407 isoform 1
NM_017757.3	NP_060227.2	zinc finger protein 407 isoform 1

ZNF407 Protein Structure

0
400
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1600
2000
2248 a.a.

Protein Preferred Names

Protein Names

zinc finger protein 407

Related Diseases

Diseases

Alias

Short Stature, Impaired Intellectual Development, Microcephaly, Hypotonia, And Ocular Anomalies

SIMHA

Simha Syndrome

Homocarnosinosis

Homocarnosinase Deficiency	Hereditary Spastic Paraplegia Mental Impairment And Thin Corpus Callosum
Spastic Paraplegia 11	Autosomal Recessive Spastic Paraplegia Type 11
Hereditary Spastic Paraplegia 11	Nakamura Osame Syndrome
Spg11	Spastic Paraplegia - Intellectual Deficit - Thin Corpus Callosum
Serum Carnosinase Deficiency

Hypotonia

Vertical Talus, Congenital

Congenital Vertical Talus	CVT
Congenital Convex Pes Valgus	Rocker-Bottom Foot Deformity
Vertical Talus	Pes Valgus, Congenital Convex
Congenital Convex Foot	Congenital Rocker-Bottom Foot
Rocker Bottom Foot	Flatfoot
Rocker-Bottom Foot	Charcot-Marie-Tooth Disease, Foot Deformity Of

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Stereotypic Movement Disorder

Stereotypy Habit Disorder	Stereotyped Repetitive Movements
Stereotyped Disorder	Stereotypes Nos
Stereotype Habit Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS16137	ZNF407 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ZNF407	VGNC	VGNC:80548
Canis familiaris	ZNF407	VGNC	VGNC:106619
Mus musculus	ZNF407	MGD	MGI:2685179
Rattus norvegicus	ZNF407	RGD	RGD:1310645
Macaca mulatta	ZNF407	VGNC	VGNC:104257

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