LTB4R2 - leukotriene B4 receptor 2 Gene

Homo sapiens

Also known as BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2

Gene ID: 56413 | Gene type: protein coding

About LTB4R2

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,310,140-24,312,038 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 238 orthologues and 17 paralogues. Broad expression in skin (RPKM 12.7), spleen (RPKM 9.3) and 21 other tissues.

Summary

Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within keratinocyte migration and signal transduction. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LTB4R2 Products(2)

mRNA	Protein	Name
NM_001164692.3	NP_001158164.1	leukotriene B4 receptor 2
NM_019839.5	NP_062813.2	leukotriene B4 receptor 2

Protein Preferred Names

Protein Names

leukotriene B4 receptor 2

LTB4 receptor JULF2

Related Diseases

Diseases

Alias

Psoriasis 5

PSORS5	Psoriasis Susceptibility 5
Psoriasis 5, Susceptibility To

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Persistent Mild Asthma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07876	LTB4R2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LTB4R2	VGNC	VGNC:31070
Mus musculus	LTB4R2	MGD	MGI:1888501
Rattus norvegicus	LTB4R2	RGD	RGD:621029
Macaca mulatta	LTB4R2	VGNC	VGNC:74314

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