Lgals1 - galectin 1 Gene

Rattus norvegicus

Gene ID: 56646 | Gene type: protein coding

About Lgals1

Summary

Enables identical protein binding activity; lactose binding activity; and laminin binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of erythrocyte aggregation; and response to isolation stress. Located in cell surface; cytosol; and nucleus. Biomarker of B-cell lymphoma; extrahepatic cholestasis; and lipoid nephrosis. Orthologous to human LGALS1 (Galectin 1). [provided by Alliance of Genome Resources, Apr 2022]

Lgals1 Products(1)

mRNA	Protein	Name
NM_019904.1	NP_063969.1	galectin-1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	10814697	RGD
enables lactose binding	IDA IDA: Inferred from direct assay	1955484	RGD
enables laminin binding	IDA IDA: Inferred from direct assay	1955484	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	10814697	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to glucose stimulus	IEP IEP: Inferred from expression pattern	19125585	RGD
involved in cellular response to organic cyclic compound	IEP IEP: Inferred from expression pattern	17316808	RGD
involved in negative regulation of cell-substrate adhesion	IDA IDA: Inferred from direct assay	1955484	RGD
involved in negative regulation of neuron projection development	IMP IMP: Inferred from mutant phenotype	17486104	RGD
involved in positive regulation of erythrocyte aggregation	IDA IDA: Inferred from direct assay	3800956	RGD
involved in response to axon injury	IEP IEP: Inferred from expression pattern	18850073	RGD
involved in response to isolation stress	IEP IEP: Inferred from expression pattern	19616040	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	17490626	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell surface	IDA IDA: Inferred from direct assay	1955484	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

galectin-1

14 kDa lectin	RL 14.5
S-Lac lectin 1	beta-galactoside-binding lectin L-14-I
gal-1	galaptin
lactose-binding lectin 1	lectin, galactose binding, soluble 1
lectin, galactoside-binding, soluble, 1

Recombinant Lgals1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74130	Galectin-1/LGALS1 Protein, Rat	P11762 (A2-E135)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07602	LGALS1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lgals1	NCBI	NCBI:3956
Mus musculus	Lgals1	NCBI	NCBI:16852

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