2. Gene
  3. MUC13 - mucin 13, cell surface associated Gene

MUC13 - mucin 13, cell surface associated Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DRCC1; MUC-13

Gene ID: 56667 | Gene type: protein coding

About MUC13

Cytogenetic location: 3q21.2 Genomic coordinates (GRCh38): 3:124,905,442-124,934,751 (from NCBI)

This gene has 5 transcripts (splice variants), 82 orthologues and 2 paralogues. Biased expression in duodenum (RPKM 317.3), small intestine (RPKM 271.9) and 4 other tissues.

Summary

Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]

MUC13 Products(1)

mRNA Protein Name
NM_033049.4 NP_149038.3 mucin-13 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
11278439 GOA
Biological Process GO Annotation Evidence Reference Source
involved in maintenance of gastrointestinal epithelium IMP
IMP: Inferred from mutant phenotype
17058067 GOA
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11278439 GOA
located in cytosol IMP
IMP: Inferred from mutant phenotype
11278439 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
11278439 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MUC13 Protein Structure

SEA

SEA: SEA domain (211 - 321)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 511 a.a.
Protein Preferred Names Protein Names

mucin-13

down-regulated in colon cancer 1

Related Diseases

Diseases Alias
Holoprosencephaly 2

HPE2

Holoprosencephaly-2

Holoprosencephaly, Type 2
Bile Duct Cystadenocarcinoma

Biliary Cystadenocarcinoma

Intrahepatic Bile Duct Cystadenocarcinoma

Intrahepatic Bile Duct Mucinous Cystic Neoplasm With An Associated Invasive Carcinoma
Lymphohistiocytoid Mesothelioma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08833 MUC13 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-E70295 N-Acetylgalactosaminyltransferase 14 / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MUC13 VGNC VGNC:68358
Mus musculus MUC13 MGD MGI:103190
Rattus norvegicus MUC13 RGD RGD:708547
Macaca mulatta MUC13 VGNC VGNC:84151
Canis familiaris MUC13 VGNC VGNC:43498
Bos taurus MUC13 VGNC VGNC:31758