PSG11 - pregnancy specific beta-1-glycoprotein 11 Gene

Homo sapiens

Also known as PSG13; PSG14; PSBG-11; PSBG-13

Gene ID: 5680 | Gene type: protein coding

About PSG11

Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38): 19:43,007,656-43,026,469 (from NCBI)

This gene has 13 transcripts (splice variants), 628 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 77.7).

Summary

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

PSG11 Products(3)

mRNA	Protein	Name
NM_001113410.2	NP_001106881.1	pregnancy-specific beta-1-glycoprotein 11 isoform 2
NM_002785.3	NP_002776.3	pregnancy-specific beta-1-glycoprotein 11 isoform 1 precursor
NM_203287.2	NP_976032.2	pregnancy-specific beta-1-glycoprotein 11 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PSG11 Protein Structure

V-set

Ig_2

0
100
200
300
335 a.a.

Protein Preferred Names

Protein Names

pregnancy-specific beta-1-glycoprotein 11

PS-beta-G-11

Related Diseases

Diseases

Alias

Mild Pre-Eclampsia

Mild Toxemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS11280	PSG11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Name
Email *

	Sorry, but the email address you supplied was invalid.