2. Gene
  3. OTOR - otoraplin Gene

OTOR - otoraplin Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FDP; MIAL1

Gene ID: 56914 | Gene type: protein coding

About OTOR

Cytogenetic location: 20p12.1 Genomic coordinates (GRCh38): 20:16,748,358-16,752,164 (from NCBI)

This gene has 3 transcripts (splice variants), 184 orthologues and 10 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. [provided by RefSeq, Jul 2013]

OTOR Products(1)

mRNA Protein Name
NM_020157.4 NP_064542.1 otoraplin precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OTOR Protein Structure

SH3_2

SH3_2: Variant SH3 domain (46 - 108)

  • 0
  • 100
  • 128 a.a.
Protein Preferred Names Protein Names

otoraplin

fibrocyte-derived protein

OTOR Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
OTOR Q9NRC9 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra
OTOR Q9NRC9 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant OTOR Proteins

Cat. No. Product Name Accession Purity
HY-P7393 Otoraplin/OTOR Protein, Human (CHO) Q9NRC9 (V18-E128) ≥95%

Related Diseases

Diseases Alias
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09866 OTOR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus OTOR RGD RGD:1305253
Felis catus OTOR VGNC VGNC:68664
Bos taurus OTOR VGNC VGNC:50240
Canis familiaris OTOR VGNC VGNC:54722
Macaca mulatta OTOR VGNC VGNC:75725
Mus musculus OTOR MGD MGI:1888678
Others OTOR NCBI