2. Gene
  3. SEMA3G - semaphorin 3G Gene

SEMA3G - semaphorin 3G Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as sem2

Gene ID: 56920 | Gene type: protein coding

About SEMA3G

This gene has 3 transcripts (splice variants), 201 orthologues and 19 paralogues. Biased expression in fat (RPKM 51.5), placenta (RPKM 13.3) and 10 other tissues.

Summary

The transcription of this gene is activated by PPAR-gamma, and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion. [provided by RefSeq, Jul 2016]

SEMA3G Products(1)

mRNA Protein Name
NM_020163.3 NP_064548.1 semaphorin-3G precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SEMA3G Protein Structure

Sema

Sema: Sema domain (60 - 502)

PSI

PSI: Plexin repeat (521 - 550)

  • 0
  • 200
  • 400
  • 600
  • 782 a.a.
Protein Preferred Names Protein Names

semaphorin-3G

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G

SEMA3G Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
SEMA3G Q9NS98 DESI2 Homo sapiens Q9BSY9
Y2H Prey Pooling
32296183
Intra
SEMA3G Q9NS98 DESI2 Homo sapiens Q9BSY9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Kallmann Syndrome

Hypogonadism With Anosmia

Kallman'S Syndrome

Anosmic Hypogonadism

Anosmic Idiopathic Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism And Anosmia

Hypogonadotropic Hypogonadism-Anosmia Syndrome

Olfacto-Genital Pathological Sequence

Familial Hypogonadism With Anosmia

Kallman Syndrome

Dysplasia Olfactogenitalis Of De Morsier

Kallmann'S Syndrome

Congenital Hypogonadotropic Hypogonadism With Anosmia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12656 SEMA3G Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SEMA3G MGD MGI:3041242
Bos taurus SEMA3G VGNC VGNC:34432
Rattus norvegicus SEMA3G RGD RGD:1306079
Felis catus SEMA3G VGNC VGNC:64991
Macaca mulatta SEMA3G VGNC VGNC:77345
Canis familiaris SEMA3G VGNC VGNC:45993